Application of Nutritional Ultrasound in the Diagnosis and Follow-up of Patients With Nutritional Risk: DRECO Study
Feasibility of Application of Nutritional Ultrasound in the Diagnosis and Follow-up of Patients With Nutritional Risk at Hospital Discharge: Study on Body Composition and Function: DRECO Study
1 other identifier
observational
1,000
1 country
25
Brief Summary
Disease-related malnutrition (DRM) can occur when there is a deficient supply of energy, protein and/or other nutrients, depending on the nutritional needs of each individual at different times of their life cycle or health or disease circumstances. This deficiency induces effects on body composition and tissue and organ function and results in clinical consequences: increased morbidity and mortality associated with different disease processes. There are techniques for nutritional assessment using assessment tools aimed at morphofunctional diagnosis of malnutrition, in addition to the classical nutritional parameters, such as weight loss, BMI, folds, circumferences, albumin, lymphocytes, cholesterol and intake. New advanced parameters are being incorporated into clinical nutrition and their incorporation into clinical practice is of increasing interest, such as measures derived from bioelectrical impedance (BIA) and phase angle (PhA), dynamometry, functional tests, CRP/prealbumin ratio and muscle ultrasound. In 2019, the GLIM criteria were published, providing a different vision of how to assess the malnourished patient. Phenotypic criteria include reduction in muscle mass (measured using validated techniques to measure body composition). The objective of the study is to highlight nutritional ultrasound for measuring muscle and functional status in order to make a more accurate diagnosis and a better prediction of complications and morbidity and mortality in this type of patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2022
Shorter than P25 for all trials
25 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2022
CompletedFirst Submitted
Initial submission to the registry
June 16, 2022
CompletedFirst Posted
Study publicly available on registry
June 27, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2022
CompletedJune 27, 2022
June 1, 2022
5 months
June 16, 2022
June 22, 2022
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Nutritional ultrasound measurements: ultrasound with 4-10 cm linear probe.
* Abdominal ultrasound: total, superficial and pre-peritoneal adipose tissue (measured in centimetres). * Muscle ultrasound: Area, circumference, axes and adipose tissue (measured in centimetres)
Patients will be followed over a period of 6 consecutive months
Secondary Outcomes (32)
Sociodemographic data:
Patients will be followed over a period of 6 consecutive months
Sociodemographic data:
Patients will be followed over a period of 6 consecutive months
Sociodemographic data:
Patients will be followed over a period of 6 consecutive months
Sociodemographic data:
Patients will be followed over a period of 6 consecutive months
Sociodemographic data:
Patients will be followed over a period of 6 consecutive months
- +27 more secondary outcomes
Eligibility Criteria
Patients over 18 years of age who, in the first week of hospital admission in medical-surgical areas, excluding critical patients, have an assessment of risk of malnutrition according to the MUST/SARC-F (R-MAPP) screening test, will be included. If the results show a moderate or high risk of malnutrition, these patients will be invited to participate in the study, and will undergo the morphofunctional assessment, an ultrasound study and the subjective global assessment (SGA).
You may qualify if:
- Patients admitted to hospital who in the first week of admission have moderate or high risk of malnutrition according to the MUST and SARC-F screening test using R-MAPP. Appendix
- Patient aged 18 to 85 years.
- Patient who agrees to participate in the study and signs the informed consent.
You may not qualify if:
- Hepatic impairment (AST/ALT 3 x upper limit of normal)
- Chronic kidney failure (GFR \<45 mL/min)
- Patient with previous ICU stay during the study admission.
- Cancer patients on palliative treatment or ECOG (Eastern Cooperative Oncology Group) ≥ 3.
- Orthopaedic disease that does not allow adequate walking
- Patients with known dementia or others not related to a significant neurological or psychiatric disorder, or any other psychological condition that may interfere with the conduct of the study.
- Patients with eating disorders
- Life expectancy of less than 6 months.
- Patients unable to adequately complete the clinical laboratory assessments required for the study protocol.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- K Access Health Projectslead
- Abbottcollaborator
Study Sites (25)
Servicio de Endocrinología y Nutrición. Complejo Hospitalario Universitario de Ferrol, A Coruña.
A Coruña, Spain
Hospital Universitario de Badajoz
Badajoz, Spain
Hospital Universitario Vall d´Hebron
Barcelona, Spain
Hospital Universitario de Basurto
Bilbao, Spain
Hospital Universitario Puerta del Mar
Cadiz, Spain
Hospital Universitario Reina Sofía
Córdoba, Spain
Hospital Universitario de Cabueñes
Gijón, Spain
Hospital Universitario Virgen de las Nieves
Granada, Spain
Hospital Universitario de Jaén
Jaén, Spain
Complejo Hospitalario Uni. Insular - Materno Infantil
Las Palmas de Gran Canaria, Spain
Hospital General Universitario Gregorio Marañón
Madrid, Spain
Hospital Universitario 12 de Octubre
Madrid, Spain
Hospital Universitario de La Princesa
Madrid, Spain
Hospital Universitario La Paz
Madrid, Spain
Clinical Management Unit of Endocrinology and Nutrition. Virgen de la Victoria Clinical Hospital, Málaga
Málaga, Spain
UGC Endocrinología y Nutrición. Hospital Regional Universitario, Málaga.
Málaga, Spain
Hospital Universitario de Navarra
Pamplona, Spain
Hospital Universitario de Canarias
Santa Cruz de Tenerife, Spain
Hospital Universitario Marqués de Valdecilla
Santander, Spain
Hospital Clínico Universitario de Santiago de Compostela
Santiago de Compostela, Spain
Hospital Universitario Virgen del Rocío
Seville, Spain
Hospital Universitario Virgen Macarena
Seville, Spain
Hospital Clínico Universitario de Valencia
Valencia, Spain
Hospital General Universitario de Valencia
Valencia, Spain
Servicio de Endocrinología y Nutrición. Hospital Clínico Universitario de Valladolid, Valladolid.
Valladolid, Spain
Related Publications (1)
Garcia Almeida JM, Bellido D, De Luis D, Guzman Rolo G, Olveira G. Protocol for a prospective cohort study on the feasibility of application of nutritional ultrasound in the diagnosis and follow-up of patients with nutritional risk at hospital discharge: study on body composition and function (DRECO). BMJ Open. 2023 Dec 9;13(12):e074945. doi: 10.1136/bmjopen-2023-074945.
PMID: 38070895DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
José Manuel García Almeida, PhD
Hospital Clínico Virgen de la Victoria, Málaga (España)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Management Unit of Endocrinology and Nutrition
Study Record Dates
First Submitted
June 16, 2022
First Posted
June 27, 2022
Study Start
January 1, 2022
Primary Completion
June 1, 2022
Study Completion
December 1, 2022
Last Updated
June 27, 2022
Record last verified: 2022-06
Data Sharing
- IPD Sharing
- Will not share