NCT07521306

Brief Summary

This retrospective study aimes to analyze the association of a number of routinely performed biomarkers with mortality in patients admitted to ICU with suspected sepsis. The study includes patients \>18 years of age, who had been admitted to the ICU with suspected sepsis. At ICU admission, baseline levels of PCT, CRP, albumin and lactate as well as WBC, neutrophil and lymphocyte counts will recorded.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started May 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2023

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2024

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

April 3, 2026

Completed
6 days until next milestone

First Posted

Study publicly available on registry

April 9, 2026

Completed
Last Updated

April 9, 2026

Status Verified

April 1, 2026

Enrollment Period

1.3 years

First QC Date

April 3, 2026

Last Update Submit

April 3, 2026

Conditions

SepsisMortalityBiomarkers

Keywords

Sepsis biomarkersMortality

Outcome Measures

Primary Outcomes (1)

  • 28-day mortality

    mortality within 28 days after intensive care admission

    28 days

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population is patients older than 18 years of age who have primary diagnoses of admission to intensive care unit are infection and suspected sepsis.

You may qualify if:

  • \>18 years of age
  • admission to the ICU with suspected sepsis

You may not qualify if:

  • ICU admission following cardiopulmonary resuscitation or cardiac surgery
  • Having a positive test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
  • Interruption of the treatment process because of transfer to another healthcare facility

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Niğde Ömer Halisdemir University Training and Research Hospital

Niğde, Niğde Province, 51200, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Sepsis

Condition Hierarchy (Ancestors)

InfectionsSystemic Inflammatory Response SyndromeInflammationPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Sümeyye Uğur

    Antalya Training and Research Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 3, 2026

First Posted

April 9, 2026

Study Start

May 1, 2023

Primary Completion

August 1, 2024

Study Completion

August 1, 2024

Last Updated

April 9, 2026

Record last verified: 2026-04

Locations

TU(1)