A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists

NCT06033950 | Recruiting Phase 3 DMC FDA Drug

• 1 other identifier: 202304CPC
• Study Type: interventional
• Target: 2,600
• Locations: 14 countries
• Sites: 176

Brief Summary

Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients with heart failure and reduced ejection fraction (HFrEF) who are intolerant or ineligible to receive treatment with steroidal mineralocorticoid receptor antagonists (sMRA).

Conditions

Heart Failure

Keywords

Reduced ejection fraction; Symptomatic heart failure

Outcome Measures

Primary Outcomes (3)

• Time to first occurrence of cardiovascular (CV) death or HF event.

  \- Time to first CV death or HF event with finerenone compared to placebo.

  Ongoing, up to ~30 months

• Number of serious adverse events

  \- Serious adverse events (excluding efficacy endpoints) with finerenone compared to placebo.

  Ongoing, up to ~30 months

• Number of adverse events leading to discontinuation of study drug.

  \- Number of adverse events leading to discontinuation of investigational product with finerenone compared to placebo.

  Ongoing, up to ~30 months

Secondary Outcomes (5)

• Timing and occurrence of total CV deaths and HF events

  Ongoing, up to ~30 months

• Timing and occurrence of total HF events

  Ongoing, up to ~30 months

• Change in Kansas City Cardiomyopathy Questionnaire Total Symptom Score (KCCQ-TSS) from baseline to Month 6.

  180 days

• Time to CV death.

  Ongoing, up to ~30 months

• Time to all-cause death.

  Ongoing, up to ~30 months

Study Arms (2)

Finerenone

EXPERIMENTAL

Drug: Finerenone

Placebo

PLACEBO COMPARATOR

Drug: Placebo

Interventions

Finerenone DRUG

Oral finerenone.

Finerenone

Placebo DRUG

Matching oral placebo.

Placebo

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Provide electronic or written informed consent, either personally or through a legally authorized representative, as permitted by local regulations
• Age ≥18 years or legal age of majority if \>18 years in the participant's country of residence
• Symptomatic HFrEF per protocol defined criteria
• Not on sMRA due to history of intolerance, contraindication, or ineligibility for treatment
• Negative pregnancy test and agreement to use adequate contraception during trial (female participants only)

You may not qualify if:

• Treatment with non-steroidal MRA (nsMRA)
• Documented prior history of severe hyperkalemia in the setting of MRA use
• eGFR \< 25 mL/min/1.73m² and / or potassium \> 5.0 mmol/L
• Acute myocardial infarction, coronary revascularization, valve replacement/repair, or implantation of a cardiac resynchronization therapy device within 30 days or planned
• Prior or planned heart transplant
• Hemodynamically significant (severe) uncorrected primary cardiac valvular disease considered by the investigator to be the primary cause of heart failure
• Symptomatic bradycardia or second- or third-degree heart block without a pacemaker
• Cardiomyopathy due to known acute inflammatory heart disease, infiltrative diseases, accumulation diseases, muscular dystrophies, cardiomyopathy with reversible causes, hypertrophic obstructive cardiomyopathy, complex congenital heart disease, or pericardial constriction
• Probable alternative cause of participant's HF
• Concomitant systemic therapy with potent cytochrome P450 isoenzyme 3A4 (CYP3A4) inhibitors, or moderate or potent CYP3A4 inducers
• Known hypersensitivity to the IP (active substance or excipients)
• Any other condition or therapy which would make the participant unsuitable for the study
• Concurrent or previous participation in another interventional clinical study using an investigational agent within 30 days prior to randomization

Sponsors & Collaborators

• Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma: collaborator
• Colorado Prevention Center: lead
• St. Luke's Hospital, Kansas City, Missouri: collaborator

Study Sites (176)

FIN-10004 Fairhope, AL Investigational Site

Fairhope, Alabama, 36532, United States

RECRUITING

Phoenix, AZ Investigative Site FIN-10115

Phoenix, Arizona, 85006, United States

RECRUITING

FIN-10401, Yuma, AZ

Yuma, Arizona, 85365, United States

RECRUITING

Chula Vista, CA Investigative Site FIN-10419

Chula Vista, California, 91910, United States

RECRUITING

Chula Vista, CA Investigative Site FIN-10111

Chula Vista, California, 91911, United States

RECRUITING

FIN-10407, Northridge, CA

Northridge, California, 91324, United States

RECRUITING

FIN-10412, Orange, CA

Orange, California, 92866, United States

RECRUITING

FIN-10070, Pamona, CA

Pomona, California, 91767, United States

RECRUITING

FIN-10024, Sacramento, CA

Sacramento, California, 95816, United States

RECRUITING

FIN-10406, San Diego, CA

San Diego, California, 91127, United States

RECRUITING

San Diego, CA Investigative Site FIN-10420

San Diego, California, 92111, United States

RECRUITING

FIN-10075 San Diego, CA Investigational Site

San Diego, California, 92243, United States

RECRUITING

San Francisco, CA Investigative Site FIN-10023

San Francisco, California, 94118, United States

RECRUITING

FIN-10423, Sherman Oaks, CA

Sherman Oaks, California, 91403, United States

RECRUITING

FON-10409, Tarzana, CA

Tarzana, California, 91356, United States

RECRUITING

FIN-10109, Van Nuys, CA

Van Nuys, California, 91405, United States

RECRUITING

FIN-10408, West Covina, CA

West Covina, California, 91790, United States

RECRUITING

FIN-10013, West Hills, CA

West Hills, California, 91307, United States

RECRUITING

FIN-10110, Aurora, CO

Aurora, Colorado, 80012, United States

RECRUITING

FIN-10001, Aurora, CO

Aurora, Colorado, 80045, United States

RECRUITING

Bradenton, FL Investigative Site FIN-10125

Bradenton, Florida, 34209, United States

RECRUITING

FIN-10104, Hialeah, FL

Hialeah, Florida, 33012, United States

RECRUITING

FIN-10028, Jacksonville, FL

Jacksonville, Florida, 32209, United States

RECRUITING

FIN-10105, Miami, FL

Miami, Florida, 33135, United States

RECRUITING

FIN-10113, Miramar, FL

Miramar, Florida, 33027, United States

RECRUITING

FIN-10019, Peoria, IL

Peoria, Illinois, 61603, United States

RECRUITING

FIN-10064, Merrillville, IN

Merrillville, Indiana, 46410, United States

RECRUITING

Cynthiana, KY Investigative Site FIN-10124

Cynthiana, Kentucky, 41031, United States

RECRUITING

FIN-10080, Lexington, KY

Lexington, Kentucky, 40503, United States

RECRUITING

Lexington, KY Investigative Site FIN-10118

Lexington, Kentucky, 40536, United States

RECRUITING

FIN-10086, Louisville, KY

Louisville, Kentucky, 40205, United States

RECRUITING

Louisville, KY Investigative Site FIN-10417

Louisville, Kentucky, 40205, United States

RECRUITING

FIN-10079, Paducah, KY

Paducah, Kentucky, 42003, United States

RECRUITING

FIN-10030, Baton Rouge, LA

Baton Rouge, Louisiana, 70808, United States

RECRUITING

FIN-10106, Hammond, LA

Hammond, Louisiana, 70403, United States

RECRUITING

FIN-10090, West Monroe, LA

West Monroe, Louisiana, 71291, United States

RECRUITING

Minneapolis, MN Investigative Site FIN-10035

Minneapolis, Minnesota, 55417, United States

RECRUITING

FIN-10002 Kansas City, MO Investigational Site

Kansas City, Missouri, 64111, United States

RECRUITING

FIN-10318, Charlotte, NC

Charlotte, North Carolina, 28207, United States

RECRUITING

Greenville, NC Investigative Site FIN-10122

Greenville, North Carolina, 27834, United States

RECRUITING

FIN-10081, Akron, OH

Akron, Ohio, 44304, United States

RECRUITING

FIN-10119, Centerville, OH

Centerville, Ohio, 45459, United States

RECRUITING

FIN- 10112, Cincinnati, OH

Cincinnati, Ohio, 45219, United States

RECRUITING

Orangeburg, SC Investigative Site FIN-10433

Orangeburg, South Carolina, 29118, United States

RECRUITING

FIN-10015 Austin, TX Investigational Site

Austin, Texas, 78705, United States

RECRUITING

FIN-10404, Denison, TX

Denison, Texas, 75020, United States

RECRUITING

FIN-10085, Houston, TX

Houston, Texas, 77030, United States

RECRUITING

Tyler, TX Investigative Site FIN-10422

Tyler, Texas, 75702, United States

RECRUITING

FIN-10405, Layton, UT

Layton, Utah, 84041, United States

RECRUITING

FIN-10053, Burlington, VT

Burlington, Vermont, 05401, United States

RECRUITING

FIN-10402, Norfolk, VA

Norfolk, Virginia, 23510, United States

RECRUITING

FIN-10093, Richmond, VA

Richmond, Virginia, 23298-5051, United States

RECRUITING

Salem, VA Investigative Site FIN-10048

Salem, Virginia, 24153, United States

RECRUITING

Milwaukee, WI Investigative Site FIN-10428

Milwaukee, Wisconsin, 53215, United States

RECRUITING

Lanus, Buenos Aires Investigative Site FIN-20024

Lanus, Buenos Aires, 1824, Argentina

RECRUITING

Rosario, Santa Fe Investigative Site FIN-20022

Rosario, Santa Fe Province, 2300, Argentina

RECRUITING

Buenos Aires Investigative Site FIN-20031

Buenos Aires, 1425, Argentina

RECRUITING

Córdoba Investigative Site FIN-20025

Córdoba, 5000, Argentina

RECRUITING

Córdoba Investigative Site FIN-20030

Córdoba, 5000, Argentina

RECRUITING

San Juan, San Juan Investigative Site FIN-20020

San Juan, J5402DIL, Argentina

RECRUITING

San Juan, San Juan Investigative Site FIN-20021

San Juan, J5402DIL, Argentina

RECRUITING

FIN-21063, Rio Branco, Acre

Rio Branco, Acre, 69915-030, Brazil

RECRUITING

FIN-21078, Maceió, Alagoas

Maceió, Alagoas, 57051-160, Brazil

RECRUITING

FIN-21072 Salvador, Bahia - BA

Salvador, Bahia - BA, 40290-000, Brazil

RECRUITING

Fortaleza, Ceará Investigative Site'FIN-21076

Fortaleza, Ceará, 60430275, Brazil

RECRUITING

Fortaleza, Ceará Investigative Site FIN-21055

Fortaleza, Ceará, 60864-190, Brazil

RECRUITING

FIN-21032, Salvador, Bahia

Salvador, Estado de Bahia, 40050-410, Brazil

RECRUITING

FIN-21028, Brasilia, Distrito Federal

Brasília, Federal District, 70390-700, Brazil

RECRUITING

FIN-21053, Aparecida de Goiânia, Goiás

Aparecida de Goiânia, Goiás, 74936-600, Brazil

RECRUITING

FIN-21003 Goiania, Goias Investigational Site

Goiânia, Goiás, 74453-200, Brazil

RECRUITING

Belo Horizonte, Minas Gerais

Belo Horizonte, Minas Gerais, 30110-934, Brazil

RECRUITING

FIN-21071, Belo Horizonte, Minas Gerais

Belo Horizonte, Minas Gerais, 30150-320, Brazil

RECRUITING

FIN-21051, Belo Horizonte, Minas Gerais

Belo Horizonte, Minas Gerais, 30220-140, Brazil

RECRUITING

Belo Horizonte, Minas Gerais Investigative Site FIN-21079

Belo Horizonte, Minas Gerais, 30220-330, Brazil

RECRUITING

FIN-21013, Belo Horizonte, Minas Gerais

Belo Horizonte, Minas Gerais, 30441-070, Brazil

RECRUITING

FIN-21056, Curitiba, Paraná

Curitiba, Paraná, 80060-900, Brazil

RECRUITING

FIN-21047, Londrina, Paraná

Londrina, Paraná, 86.038-350, Brazil

RECRUITING

FIN-21021, Recife, Pernambuco

Recife, Pernambuco, 50100-040, Brazil

RECRUITING

Recife, Pernambuco Investigative Site FIN-21086

Recife, Pernambuco, 51.110-160, Brazil

RECRUITING

FIN-21061, Recife, Pernambuco

Recife, Pernambuco, 52010-075, Brazil

RECRUITING

Teresina, Piaui Investigative Site FIN-21050

Teresina, Piauí, 64001-450, Brazil

RECRUITING

FIN-21001, Recife, Recife

Recife, Recife, 50720-110, Brazil

RECRUITING

FIN-21016, Rio De Janeiro, Rio De Janeiro

Rio de Janeiro, Rio de Janeiro, 20551-030, Brazil

RECRUITING

FIN-21014, Rio de Janeiro, Rio de Janeiro

Rio de Janeiro, Rio de Janeiro, 22240-006, Brazil

RECRUITING

FIN-21024, Natal, Rio Grande do Norte

Natal, Rio Grande do Norte, 5902050, Brazil

RECRUITING

FIN-21008, Caxias do Sul, Rio Grande do Sul

Caxias do Sul, Rio Grande do Sul, 95070-560, Brazil

RECRUITING

FIN-21019, Porto Alegre, Rio Grande do Sul

Porto Alegre, Rio Grande do Sul, 90840-440, Brazil

RECRUITING

FIN-21007, Joinville, Santa Catarina

Joinville, Santa Catarina, 89200-000, Brazil

RECRUITING

FIN-21058, Aracaju, Sergipe

Aracaju, Sergipe, 49055-210, Brazil

RECRUITING

FIN-21004 Braganca Paulista, Sao Paulo

Bragança Paulista, São Paulo, 12916542, Brazil

RECRUITING

Campinas, São Paulo Investigative Site' FIN-21083

Campinas, São Paulo, 13083-190, Brazil

RECRUITING

FIN-21068, Guarulhos, São Paulo

Guarulhos, São Paulo, 07197-000, Brazil

RECRUITING

FIN-21005, Itaquera, São Paulo

Itaquera, São Paulo, 08270-120, Brazil

RECRUITING

FIN-21010, Osasco, São Paulo

Osasco, São Paulo, 06013-070, Brazil

RECRUITING

FIN-21011, Presidente Prudente, São Paulo

Presidente Prudente, São Paulo, 19050-680, Brazil

RECRUITING

FIN-21043, Santo André, São Paulo

Santo André, São Paulo, 09090790, Brazil

RECRUITING

São Carlos, São Paulo Investigative Site FIN-21075

São Carlos, São Paulo, 13566-448, Brazil

RECRUITING

São José dos Campos, São Paulo Investigative Site'FIN-21081

São José dos Campos, São Paulo, 12243000, Brazil

RECRUITING

FIN-21074, São Paulo, São Paulo

São Paulo, São Paulo, 01229-010, Brazil

RECRUITING

FIN-21037, São Paulo, São Paulo

São Paulo, São Paulo, 01323-001, Brazil

RECRUITING

FIN-21048, São Paulo, São Paulo

São Paulo, São Paulo, 04004-30, Brazil

RECRUITING

FIN-21049 Sao Paulo, Sao Paulo

São Paulo, São Paulo, 05652-900, Brazil

RECRUITING

FIN-21031, Votuporanga, São Paulo

Votuporanga, São Paulo, 15505-189, Brazil

RECRUITING

Rio de Janeiro Investigative Site FIN-21034

Rio de Janeiro, 22280-003, Brazil

RECRUITING

São Paulo Investigative Site FIN-21066

São Paulo, 05403-000, Brazil

RECRUITING

Calgary, AB Investigative Site FIN-11009

Calgary, Alberta, T2N 1N4, Canada

RECRUITING

FIN-11028, Edmonton, AB

Edmonton, Alberta, T5H 4B9, Canada

RECRUITING

FIN-11011, Edmonton, AB

Edmonton, Alberta, T6G 2B7, Canada

RECRUITING

FIN-11020, North Vancouver, BC

North Vancouver, British Columbia, V7M 2H4, Canada

RECRUITING

FIN-11012 Surrey, BC Investigational Site

Surrey, British Columbia, V3V OC6, Canada

RECRUITING

FIN-11025, Victoria, BC

Victoria, British Columbia, V8R 1B2, Canada

RECRUITING

FIN-11006, Winnipeg, MB

Winnipeg, Manitoba, R2H 2A6, Canada

RECRUITING

FIN-11016, Sudbury, ON

Greater Sudbury, Ontario, P3E 5J1, Canada

RECRUITING

FIN-11024, Kingston, ON

Kingston, Ontario, K7L 2V7, Canada

RECRUITING

FIN-11010, London, ON

London, Ontario, N6A 5A5, Canada

RECRUITING

FIN-11007, North York, ON

North York, Ontario, M6B 3H7, Canada

RECRUITING

FIN-11008, Toronto, ON

Toronto, Ontario, M4N 3M5, Canada

RECRUITING

FIN-11019, Toronto, ON

Toronto, Ontario, M5B 1W8, Canada

RECRUITING

FIN-11005, Sherbrooke, QC

Sherbrooke, Quebec, J1H 5N4, Canada

RECRUITING

FIN-30001, Zagreb, Croatia

Zagreb, Croatia, 10000, Croatia

RECRUITING

FIN-30003, Zagreb, Croatia

Zagreb, Croatia, 10000, Croatia

RECRUITING

FIN-30007, Zagreb, Croatia

Zagreb, Croatia, 10000, Croatia

RECRUITING

Cepin Investigative Site FIN-30010

Čepin, 31431, Croatia

RECRUITING

FIN-30004, Krapinske Toplice

Krapinske Toplice, 49217, Croatia

RECRUITING

Osijek Investigative Site FIN-30008

Osijek, 31000, Croatia

RECRUITING

FIN-31002, Brno, Czech Republic

Brno, Czech Republic, 612 00, Czechia

RECRUITING

Athens, Attica Investigative Site FIN-33004

Athens, Attica, 115 27, Greece

RECRUITING

Athens, Attica Investigative Site FIN-33009

Athens, Attica, 155 62, Greece

RECRUITING

Chaidari, Attica Investigative Site FIN-33006

Chaïdári, Attica, 124 62, Greece

RECRUITING

Kallithea, Attica Investigative Site FIN-33010

Kallithea, Attica, 176 74, Greece

RECRUITING

Nea Ionia, Attica Investigative Site FIN-33007

Nea Ionia, Attica, 142 33, Greece

RECRUITING

Thessaloniki, Central Macedonia Investigative Site FIN-33002

Thessaloniki, Central Macedonia, 546 36, Greece

RECRUITING

Alexandroupolis, Evros Investigative Site FIN-33012

Alexandroupoli, Evros, 68100, Greece

RECRUITING

FIN-34004, Nyiregyhaza, Hungary

Nyíregyháza, Hungary, 4400, Hungary

RECRUITING

Budapest Investigative Site FIN-34001

Budapest, 1122, Hungary

RECRUITING

Gyöngyös Investigative Site FIN-34011

Gyöngyös, 3200, Hungary

RECRUITING

Pecs Investigative Site FIN-34006

Pécs, 7624, Hungary

RECRUITING

Brescia, BS Investigative Site FIN-35006

Brescia, BS, 25123, Italy

RECRUITING

FIN-35003, Loc. Germaneto - Catanzaro, CZ

Germaneto, CZ, 88100, Italy

RECRUITING

FIN-57002, Sapporo, Hokkaido

Sapporo, Hokkaido, 060-8648, Japan

RECRUITING

FIN-57009, Isehara, Kanagawa

Isehara, Kanagawa, 259-1193, Japan

RECRUITING

FIN-57006, Sagamiharam, Kanagawa

Sagamihara, Kanagawa, 252-5188, Japan

RECRUITING

FIN-57001, Kyoto, Kyoto

Kyoto, Kyoto, 606-8507, Japan

RECRUITING

FIN-57003, Sendai, Miyagi

Sendai, Miyagi, 980-8574, Japan

RECRUITING

FIN-57004, Osaka, Osaka

Osaka, Osaka, 530-0005, Japan

RECRUITING

FIN-57007, Suita, Osaka

Suita, Osaka, 564-8565, Japan

RECRUITING

FIN-57009, Ota-ku, Tokyo

Ōta-ku, Tokyo, 143-8540, Japan

RECRUITING

FIN-57005, Iwakuni, Yamaguchi

Iwakuni, Yamaguchi, 740-8510, Japan

RECRUITING

FIN-37006, Lublin, Lublin

Lublin, Lublin Voivodeship, 20-011, Poland

RECRUITING

FIN-37002, Oswiecim, Oswiecim

Oświęcim, Oswiecim, 32-600, Poland

RECRUITING

Kraków Investigative Site FIN-37007

Krakow, 30-702, Poland

RECRUITING

Łódź Investigative Site FIN-37003

Lodz, 92-213, Poland

RECRUITING

Tychy, Investigative Site FIN-37009

Tychy, 43-100, Poland

RECRUITING

Gerona, Cataluña Investigative Site FIN-38017

Girona, Catalonia, 17007, Spain

RECRUITING

A Coruña, Galicia Investigative Site FIN-38004

A Coruña, Galicia, 15006, Spain

RECRUITING

FIN-38008, Santiago de Compostela, Galicia

Santiago de Compostela, Galicia, 15706, Spain

RECRUITING

FIN-38002, Madrid, Madrid

Madrid, Madrid, 28034, Spain

RECRUITING

FIN-38011, Madrid, Madrid

Madrid, Madrid, 28046, Spain

RECRUITING

FIN-38006, Majadahonda, Madrid

Majadahonda, Madrid, 28222, Spain

RECRUITING

FIN-38012, Málaga, Málaga

Málaga, Málaga, 29010, Spain

RECRUITING

FIN-38009, Manises, Valencia

Manises, Valencia, 46940, Spain

RECRUITING

FIN-38001, Valencia, Valencia

Valencia, Valencia, 46026, Spain

RECRUITING

FIN-38007, Valencia, Valencia

Valencia, Valencia, 46026, Spain

RECRUITING

Barcelona Investigative Site FIN-38010

Barcelona, 08907, Spain

RECRUITING

Kandy, Central Province Investigative Site FIN-54001

Kandy, Central Province, 2000, Sri Lanka

RECRUITING

Jaffna, Northern Province Investigative Site FIN-54014

Jaffna, Northern Province, 40000, Sri Lanka

RECRUITING

Kurunegala, Northwestern Province Investigative Site FIN-54013

Kurunegala, Northwestern Province, 60000, Sri Lanka

RECRUITING

Colombo, Western Province Investigative Site FIN-54004

Colombo, Western Province, 01000, Sri Lanka

RECRUITING

Colombo, Western Province Investigative Site FIN-54006

Colombo, Western Province, 01000, Sri Lanka

RECRUITING

Colombo, Western Province Investigative Site FIN-54007

Colombo, Western Province, 10350, Sri Lanka

RECRUITING

Negombo, Western Province Investigative Site FIN-54002

Negombo, Western Province, 11500, Sri Lanka

RECRUITING

Ragama, Western Province Investigative Site FIN-54008

Ragama, Western Province, 11010, Sri Lanka

RECRUITING

FIN-39007, Bristol, UK

Bristol, UK, BS10 5NB, United Kingdom

RECRUITING

London, UK

London, UK, SW17 0QT, United Kingdom

RECRUITING

FIN-39001, Glasgow, UK

Glasgow, G4 0SF, United Kingdom

RECRUITING

FIN-39006, Southampton, UK

Southampton, SO16 6YD, United Kingdom

RECRUITING

MeSH Terms

Conditions

Heart Failure

Interventions

finerenone

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Central Study Contacts

Marc Bonaca

CONTACT

(303) 860-9900; info@cpcmed.org

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 29, 2023
• First Posted: September 13, 2023
• Study Start: August 20, 2024
• Primary Completion: August 1, 2026
• Study Completion (Estimated): January 1, 2028
• Last Updated: July 10, 2026

Record last verified: 2026-07

Locations

US (54); BR (44); CA (14); HU (4); JP (9); AR (7); PL (5); SR (8); CZ (1); GR (7); ES (11); IT (2); GB (4); CR (6)