Key Insights

Highlights

Success Rate

89% trial completion (above average)

Published Results

489 trials with published results (13%)

Research Maturity

1853 completed trials (50% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

6.2%

230 terminated out of 3722 trials

Success Rate

89.0%

+2.5% vs benchmark

Late-Stage Pipeline

12%

451 trials in Phase 3/4

Results Transparency

26%

489 of 1853 completed with results

Key Signals

489 with results89% success230 terminated

Data Visualizations

Phase Distribution

2,478Total
Not Applicable (1567)
Early P 1 (19)
P 1 (168)
P 2 (273)
P 3 (186)
P 4 (265)

Trial Status

Completed1,853
Unknown575
Recruiting528
Terminated230
Not Yet Recruiting192
Active Not Recruiting141

Trial Success Rate

89.0%

Benchmark: 86.5%

Based on 1853 completed trials

Clinical Trials (3722)

Showing 20 of 20 trials
NCT02963272Not ApplicableCompletedPrimary

ST2 for the Management of Heart Failure - STADE-HF

NCT06280820Enrolling By InvitationPrimary

Multi-Scale Analysis of Phenotypes in Heart Failure (MAP-HEART)

NCT03514108Phase 4CompletedPrimary

DANHEART (H-HeFT and Met-HeFT)

NCT07640022Not ApplicableNot Yet RecruitingPrimary

Optimization of Coronary Sinus Lead Placement for CRT Delivery in Non-LBBB or Narrow LBBB Patterns Using Multiparametric 82Rubidium PET-CT Scan Analysis and Cardiac CT Venography

NCT06526195Not ApplicableRecruitingPrimary

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

NCT07574593Not ApplicableRecruitingPrimary

NORM-HF Pivotal Study

NCT07634419Not ApplicableNot Yet Recruiting

Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress: the Lift RCT

NCT06935370Phase 3RecruitingPrimary

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

NCT05677100Not ApplicableRecruitingPrimary

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

NCT07634822Not Yet RecruitingPrimary

Heart Failure and Postoperative Outcome in Surgery - a National Registry Study

NCT04405583RecruitingPrimary

The AFteR Registry - Follow-up Study to Monitor the Efficacy and Safety of the Occlutech AFR in Heart Failure Patients

NCT06979726Phase 4RecruitingPrimary

Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure

NCT05741658Phase 4Enrolling By InvitationPrimary

The Fontan Dapagliflozin Pilot Study

NCT07632027Not ApplicableNot Yet Recruiting

Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine Position

NCT07631780Not ApplicableNot Yet Recruiting

SURE-HF: Urinary Sodium-Guided Diuretic Therapy in Heart Failure

NCT05924802Not ApplicableActive Not RecruitingPrimary

Physiological Effects Ketone Ester in Heart

NCT04347759Not ApplicableCompletedPrimary

Symptom Care at Home-Heart Failure

NCT01918215Not ApplicableCompletedPrimary

Cardiac Magnetic Resonance GUIDEd Management of Mild-moderate Left Ventricular Systolic Dysfunction.

NCT07631156Phase 4Not Yet Recruiting

STEPwise De-escalation and Optimizing Withdrawal of ARNI and SGLT2i in Normalized Heart Failure

NCT07626853CompletedPrimary

Digital Literacy of Chronic Heart Failure Patients

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