NCT05981820

Brief Summary

Creatine is an ergogenic aid with positive effects on muscle and performance. The aim of the study was to determine whether there is a difference between the effects of creatine supplementation taken together with Wingate-based HIIT on anaerobic power, leg strength, heart rate variability and body composition. In the study, Wingate-based HIIT program was applied three days a week for six weeks. Anaerobic power (Wingate anaerobic power test), heart rate variability (Polar H10 chest band), leg strength (back and leg dynamometer) and body composition (PlusAvis 333) measurements of the participants were made 1 week before the training program started and the week after the training program ended. Twenty physically active adult men aged 18-30 were voluntarily included for the study. Participants were divided into two groups: Wingate-based HIIT with creatine supplementation (K-HIIT) and Wingate-based HIIT only (HIIT). As a result of the analysis, it was seen that creatine supplementation taken together with wingate-based HIIT had an effect and increased on the anaerobic power parameters, peak power, average power and minimum power values, and leg strength. In addition, it was determined that heart rate variability parameters improved heart rate (HR, beat/min) and low frequency (LF, ms2) values, but did not cause any change in body composition. Comparing and investigating the effects of different HIIT methods on anaerobic power, leg strength, heart rate variability and body composition will increase the generalizability of the study.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2022

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 10, 2022

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2022

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2023

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

April 26, 2023

Completed
3 months until next milestone

First Posted

Study publicly available on registry

August 8, 2023

Completed
Last Updated

August 8, 2023

Status Verified

July 1, 2023

Enrollment Period

5 months

First QC Date

April 26, 2023

Last Update Submit

July 30, 2023

Conditions

Keywords

ergogenic aidsHIITcreatineperformance

Outcome Measures

Primary Outcomes (2)

  • Wingate anaerobic power test

    The Wingate anaerobic power test will be performed using a bicycle ergometer.First, a four-minute warm-up protocol with a bicycle ergometer at 60-80 rpm pedal speed and 50 W workload will be applied. Weights of 7.5% kilograms of their body weight for each participant will be placed on the pan of the bicycle ergometer and anaerobic power testing will be initiated. When they reach the pedal speed to 150 rpm, the test will start. Their maximal effort during 30-seconds will be collected. The Wingate software will be used in which the program set up with the ergometers. Information about the relevant power parameters during the test will be transmitted to the software program on the computer. All power parameters such as both absolute and relative peak power, minimum power, average power etc. will be calculated by the software program automatically.

    two months

  • Leg strength

    Back and leg dynamometer (Takei-Back \& Lift, Japan) will be used to measure leg strength. Participants will be placed their feet on the dynamometer stand. The legs will be bent at 15 angles, the body slightly forward, and the back straight. The participants will pull the dynamometer bar, which they grasped with their hands, using only their legs, without changing their current position, until the knees will be extended. Participants will repeat this trial twice, and the best value for each participant will be recorded.

    two months

Study Arms (2)

HIIT group

EXPERIMENTAL

This group will only participate Wingate-based HIIT training. In the first three weeks: * Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes * Wingate-based HIIT: HIIT 4 sets of 12x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set * Cool-down: 4 minutes of passive rest between sets In the last three weeks: * Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes * Wingate-based HIIT: HIIT 5 sets of 20x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets

Other: HIIT training

HIIT + creatine group

EXPERIMENTAL

The HIIT + creatine group will participate the same Wingate-based HIIT training in addition to consume 10 g of creatine supplementation. Participants in this group will use 10 g of creatine monohydrate by dissolved in 200 ml of water. Creatine supplementation will be taken in two doses of five grams, 30 minutes before and after training.

Dietary Supplement: CreatineOther: HIIT training

Interventions

CreatineDIETARY_SUPPLEMENT

To observe the effects of creatine in the study, 10 g of creatine supplementation was taken only on training days during the study period. Participants used 10 g of creatine monohydrate by dissolved in 200 ml of water. Creatine supplementation was taken in two doses of five grams, 30 minutes before and after training.

HIIT + creatine group

In the first three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 4 sets of 12x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets In the last three weeks: Warm-up: Warm-up at 70 rpm for 4 minutes, including 2-3 seconds of maximal sprint at 1.30 and 2.30 minutes Wingate-based HIIT: HIIT 5 sets of 20x15 seconds of maximal repetitions with 15 seconds of passive rest between reps in each set Cool-down: 4 minutes of passive rest between sets

HIIT + creatine groupHIIT group

Eligibility Criteria

Age18 Years - 30 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • having no health and communication problem
  • using no drugs or ergogenic aids
  • being physically active adult men aged 18-30 years

You may not qualify if:

  • using any drugs or ergogenic aids
  • having any musculoskeletal problem

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ankara University Spor Bilimleri Fakultesi

Gölbaşı, Ankara, 06830, Turkey (Türkiye)

Location

MeSH Terms

Interventions

Creatine

Intervention Hierarchy (Ancestors)

GuanidinesAmidinesOrganic ChemicalsAmino AcidsAmino Acids, Peptides, and Proteins

Study Officials

  • Dicle Aras

    Ankara University Faculty of Sport Sciences

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

April 26, 2023

First Posted

August 8, 2023

Study Start

March 10, 2022

Primary Completion

August 1, 2022

Study Completion

January 15, 2023

Last Updated

August 8, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations