Creatine Supplementation in Female Collegiate Dancers

NCT05109039 | Completed

• 1 other identifier: 21-181
• Study Type: interventional
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be a 6 week creatine supplementation intervention with performance familiarization and pre and post testing. Participants will report to the human performance laboratory (HPL) for baseline to read and sign an informed consent explaining the procedures and potential risks and benefits of participation. Participants will then complete a physical activity readiness questionnaire (PAR-Q) prior to performing any physical tasks. Participants will also be asked to complete testing below in the order described. Participants will become familiar with the pre/post performance tests, which include isokinetic testing, medicine ball throw, vertical jump, and Wingate testing. Twenty-four hours following visit 1, participants will return to the HPL for visit 2 where they will undergo a second familiarization session for the isokinetic testing and Wingate testing only - these two tests require individuals to provide maximal physical efforts and research suggests that participants should perform multiple familiarization trials before beginning experimental trials. At least 72 hours following visit 2, participants will return to the HPL for visit 3 to perform the baseline performance assessments. Following the baseline assessments, participants will be divided into two supplementation groups: creatine and placebo (maltodextrin). These groups will be randomized and matched based on body mass, hours of dance training per week, meat intake, and menstrual cycle phase. Participants will be asked to consume one of the two supplements daily for 42 consecutive days and maintain their regular dance training and eating behaviors. Participants will report to the HPL daily to receive their supplement between the hours of 12pm and 2pm. Following the last day of supplement consumption, participants will report to the HPL to perform post-testing assessments which will be identical to pre testing.

Conditions

Creatine

Keywords

creatine, body composition, dancer, cognition

Outcome Measures

Primary Outcomes (9)

• Change in fat mass from baseline after 42 days

  Dual energy x-ray absorptiometry used to assess fat mass (% and kg)

  Change from baseline fat mass at 42 days

• Change in lean mass from baseline after 42 days

  Dual energy x-ray absorptiometry used to assess lean mass (% and kg)

  Change from baseline lean mass at 42 days

• Change in visceral adipose tissue from baseline after 42 days

  Dual energy x-ray absorptiometry used to assess visceral adipose tissue (cm2)

  Change from baseline visceral adipose tissue at 42 days

• Change in peak muscular strength from baseline after 42 days

  Cybex isokinetic dynamometry used to assess peak muscular strength (W)

  Change from baseline peak muscular strength at 42 days

• Change in peak vertical jump height from baseline after 42 days

  Cybex isokinetic dynamometry used to assess vertical jump height (in)

  Change from baseline peak vertical jump height at 42 days

• Change in upper body muscular power from baseline after 42 days

  Seated medicine ball toss used to assess upper body muscular power (in)

  Change from baseline upper body muscular power at 42 days

• Change in muscular power from baseline after 42 days

  Wingate anaerobic power test used to assess muscular power (W)

  Change from baseline muscular lower at 42 days

• Change in depression, anxiety and stress score from baseline after 42 days

  Depression, anxiety and stress scale (from 0, normal to 42, extremely severe) used to assess depression, anxiety and stress

  Change from baseline depression, anxiety and stress at 42 days

• Change in cognitive performance from baseline after 42 days

  NIH Toolbox for the assessment of Neurological and Behavioral Function ipad application to assess fluid cognitive measures including executive function, attention, episodic memory, processing speed, and working memory.

  Change from baseline cognitive performance at 42 days

Study Arms (2)

Creatine Supplementation

EXPERIMENTAL

Dietary Supplement: Creatine

Placebo Supplementation

PLACEBO COMPARATOR

Dietary Supplement: Placebo

Interventions

Creatine DIETARY_SUPPLEMENT

Participants will consume 0.1g/kg body weight of creatine with 0.1g/kg body weight of maltodextrin for 42 consecutive days

Creatine Supplementation

Placebo DIETARY_SUPPLEMENT

Participants will consume 0.2g/kg body weight of maltodextrin for 42 consecutive days

Placebo Supplementation

Eligibility Criteria

• Age: 18 Years - 24 Years
• Sex: female
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Collegiate dance major or minor

You may not qualify if:

• Injured within the past 6 months
• Currently consuming creatine supplements

Sponsors & Collaborators

• University of Idaho: lead

Study Sites (1)

University of Idaho

Moscow, Idaho, 83844, United States

Location

MeSH Terms

Interventions

Creatine

Intervention Hierarchy (Ancestors)

Guanidines; Amidines; Organic Chemicals; Amino Acids; Amino Acids, Peptides, and Proteins

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: October 26, 2021
• First Posted: November 5, 2021
• Study Start: September 27, 2021
• Primary Completion: January 30, 2022
• Study Completion: January 30, 2022
• Last Updated: August 15, 2022

Record last verified: 2022-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)