NCT05916352

Brief Summary

It was aimed to apply caffeine supplement to elite basketball players and to investigate the effects of this supplement on upper extremity performance, lactic acid level and fatigue. The investigators also aimed to investigate the effects of blood lactate level on performance and fatigue.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 4, 2022

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 14, 2022

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 6, 2023

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

June 7, 2023

Completed
16 days until next milestone

First Posted

Study publicly available on registry

June 23, 2023

Completed
Last Updated

August 2, 2023

Status Verified

July 1, 2023

Enrollment Period

3 months

First QC Date

June 7, 2023

Last Update Submit

July 31, 2023

Conditions

Sportive PerformanceCaffeine

Keywords

CaffeinePerformanceLactic AcidBasketballFatigue

Outcome Measures

Primary Outcomes (1)

  • Blood Lactate Level

    Lactic acid level in the blood

    2 hours

Secondary Outcomes (4)

  • Reaction Time

    5 minutes

  • Anaerobic Power

    5 minutes

  • Muscular Endurance

    5 minutes

  • Fatigue

    1 minute

Study Arms (2)

Caffeine Group

ACTIVE COMPARATOR

5 mg/kg caffein supplement will be given

Dietary Supplement: Caffeine Supplement

Placebo Group

PLACEBO COMPARATOR

Placebo will be given

Dietary Supplement: Caffeine Supplement

Interventions

Caffeine SupplementDIETARY_SUPPLEMENT

Caffeine tablet

Caffeine GroupPlacebo Group

Eligibility Criteria

Age19 Years - 44 Years
Sexmale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Elite basketball players aged 19-44
  • Individuals with caffeine consumption below 2 mg per kg per day

You may not qualify if:

  • Individuals with systemic disease affecting the musculoskeletal system
  • Individuals using supplements containing caffeine
  • Individuals with any diagnosed neurological or orthopedic disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cyprus International University

Mersin, Turkey (Türkiye)

Location

Related Publications (8)

  • Ben Abdelkrim N, Castagna C, El Fazaa S, Tabka Z, El Ati J. Blood metabolites during basketball competitions. J Strength Cond Res. 2009 May;23(3):765-73. doi: 10.1519/JSC.0b013e3181a2d8fc.

    PMID: 19387403RESULT

  • Spriet LL. Exercise and sport performance with low doses of caffeine. Sports Med. 2014 Nov;44 Suppl 2(Suppl 2):S175-84. doi: 10.1007/s40279-014-0257-8.

    PMID: 25355191RESULT

  • Burke LM. Practical Issues in Evidence-Based Use of Performance Supplements: Supplement Interactions, Repeated Use and Individual Responses. Sports Med. 2017 Mar;47(Suppl 1):79-100. doi: 10.1007/s40279-017-0687-1.

    PMID: 28332111RESULT

  • Caravan I, Sevastre Berghian A, Moldovan R, Decea N, Orasan R, Filip GA. Modulatory effects of caffeine on oxidative stress and anxiety-like behavior in ovariectomized rats. Can J Physiol Pharmacol. 2016 Sep;94(9):961-72. doi: 10.1139/cjpp-2015-0502. Epub 2016 Apr 16.

    PMID: 27333093RESULT

  • Chia JS, Barrett LA, Chow JY, Burns SF. Effects of Caffeine Supplementation on Performance in Ball Games. Sports Med. 2017 Dec;47(12):2453-2471. doi: 10.1007/s40279-017-0763-6.

    PMID: 28741186RESULT

  • Grgic J, Trexler ET, Lazinica B, Pedisic Z. Effects of caffeine intake on muscle strength and power: a systematic review and meta-analysis. J Int Soc Sports Nutr. 2018 Mar 5;15:11. doi: 10.1186/s12970-018-0216-0. eCollection 2018.

    PMID: 29527137RESULT

  • Sant'Ana J, Franchini E, da Silva V, Diefenthaeler F. Effect of fatigue on reaction time, response time, performance time, and kick impact in taekwondo roundhouse kick. Sports Biomech. 2017 Jun;16(2):201-209. doi: 10.1080/14763141.2016.1217347. Epub 2016 Sep 5.

    PMID: 27592682RESULT

  • San Juan AF, Lopez-Samanes A, Jodra P, Valenzuela PL, Rueda J, Veiga-Herreros P, Perez-Lopez A, Dominguez R. Caffeine Supplementation Improves Anaerobic Performance and Neuromuscular Efficiency and Fatigue in Olympic-Level Boxers. Nutrients. 2019 Sep 5;11(9):2120. doi: 10.3390/nu11092120.

    PMID: 31492050RESULT

MeSH Terms

Conditions

Fatigue

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Model Details: The research is a double-blind randomized controlled comparative cross-sectional study.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Academic Professor

Study Record Dates

First Submitted

June 7, 2023

First Posted

June 23, 2023

Study Start

July 4, 2022

Primary Completion

October 14, 2022

Study Completion

June 6, 2023

Last Updated

August 2, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will share

The individual participant data obtained from the participants will be shared in the form of thesis and scientific articles.

Shared Documents
STUDY PROTOCOL
Time Frame
Starting in July 2023
Access Criteria
The results of the study will be shared in the form of scientific articles by making appropriate statistical analyzes.

Locations

TU(1)