NCT05911490

Brief Summary

This study primarily aimed to investigate effects of breaking up prolonged sitting with intermittent brisk walking in healthy young individuals on (1) post-trial human behaviours including energy intake and physical activity under free-living conditions and (2) cognitive performance in a simulated workplace environment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Dec 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 20, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 29, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 29, 2020

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

May 20, 2023

Completed
1 month until next milestone

First Posted

Study publicly available on registry

June 22, 2023

Completed
Last Updated

June 22, 2023

Status Verified

June 1, 2023

Enrollment Period

9 months

First QC Date

May 20, 2023

Last Update Submit

June 9, 2023

Conditions

Energy BalancePhysical Activity LevelCognitionMetabolic Health

Keywords

Breaking up sittingEating behaviourSpontaneous physical activityExecutive functionEnergy balance

Outcome Measures

Primary Outcomes (4)

  • Physical activity level

    Changes in physical activity level (steps) in the free-living conditions

    480 minutes

  • Energy intake

    Changes in energy intake (kcal) in the free-living conditions

    480 minutes

  • Cognitive performance

    Changes in cognitive performance (% changes in accuracy) including Task Switching and Flanker tasks

    320 minutes

  • Cognitive function

    Changes in cognitive performance (% changes in reaction time) Task Switching and Flanker tasks

    320 minutes

Secondary Outcomes (4)

  • Postprandial glucose concentrations

    320 minutes

  • Blood pressure

    320 minutes

  • Visual analogue scale (VAS)

    320 minutes

  • Continuous glucose monitoring

    320 minutes

Study Arms (2)

Prolonged sitting

ACTIVE COMPARATOR

Participants sat on a chair during the trial in the laboratory.

Behavioral: Prolonged sitting

Breaking prolonged sitting

EXPERIMENTAL

Participants walked regularly during the trial in the laboratory.

Behavioral: Breaking prolonged sitting

Interventions

Prolonged sittingBEHAVIORAL

In the laboratory, after consuming 1st meal, participants sat on a chair for 180 min. After 180 min, the 2nd meal was provided. After finishing the 2nd meal, participants sat on a chair for another 120 min. After data collection was completed in the laboratory, participants were asked to keep wearing the same pedometer and to record any food and liquid consumption for the rest of the day (until midnight) under free-living conditions.

Prolonged sitting
Breaking prolonged sittingBEHAVIORAL

In the laboratory, after consuming 1st meal, participants walked 2 min on a treadmill every 20 minutes for the following 180 min. For the remainder of the time participants sat on the chair. After 180 min, the 2nd meal was provided. After finishing the 2nd meal, participants continued 2 min of walking every 20 min for the following 120 min. After data collection was completed in the laboratory, participants were asked to keep wearing the same pedometer and to record any food and liquid consumption for the rest of the day (until midnight) under free-living conditions.

Breaking prolonged sitting

Eligibility Criteria

Age20 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Without current and any history of brain injury, neurological disorder, cardiometabolic related diseases, diabetes or cancers.
  • Weight stable (not self-reported weight change ± 3 kg at least 3 months)
  • Body mass index (BMI) ranging between 18.5 to 27 kg/m2
  • Can walk safely on a treadmill

You may not qualify if:

  • Smokers, post-menopausal female, and volunteers who used any medications that could influence metabolic and inflammatory responses.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

National Taiwan Normal University

Taipei, Taiwan

Location

MeSH Terms

Conditions

Feeding Behavior

Condition Hierarchy (Ancestors)

Behavior, AnimalBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 20, 2023

First Posted

June 22, 2023

Study Start

December 20, 2019

Primary Completion

September 29, 2020

Study Completion

September 29, 2020

Last Updated

June 22, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will not share

Locations

TW(1)