Falciformopexy for Treatment Perforated Peptic Ulcer.

NCT05715450 | Not Yet Recruiting

• 1 other identifier: Falciform ligament on PPU
• Study Type: interventional
• Target: 25
• Locations: 0 countries
• Sites: N/A

Brief Summary

Use the falciform ligament flap for the treatment of perforated peptic ulcer

Conditions

Perforated Peptic Ulcer

Outcome Measures

Primary Outcomes (1)

• Falciformopexy for Treatment Perforated Peptic Ulcer

  The aim is to decrease incidence of leakage from the perforated peptic ulcer by using the falciform ligament for repair of the perforated peptic ulcer. Firstly, the investigator will seek to repair the perforation using suture to approximate edges then use falciform ligament as a secound layer to ensure security and prevent postoperative leakage that will lead to peritonitis and death.

  Baseline

Study Arms (1)

Falciformopexy for Treatment Perforated Peptic Ulcer

OTHER

Use falciform ligament flap for repair perforated peptic ulcer

Procedure: Falciformopexy for Treatment Perforated Peptic Ulcer

Interventions

Falciformopexy for Treatment Perforated Peptic Ulcer PROCEDURE

use the falciform ligament on perforated peptic ulcer

Falciformopexy for Treatment Perforated Peptic Ulcer

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• \- Any cases presented with PPU within age from 18 till 70 years.

You may not qualify if:

• malignancy.
• Previous GIT and liver surgery.
• nonoperative treatment.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Fry DE, Richardson JD, Flint LM Jr. Closure of an acute perforated peptic ulcer with the falciform ligament. Arch Surg. 1978 Oct;113(10):1209-10. doi: 10.1001/archsurg.1978.01370220095016.

  PMID: 708243 BACKGROUND

• Son TQ, Hoc TH, Huong TT, Long VD, Tung TT, Quyet NC, Panha L, Van Chi N. Outcomes of surgical management of peptic ulcer perforation using the falciform ligament: A cross-sectional study at a single centre in Vietnam. Ann Med Surg (Lond). 2021 Jun 16;67:102477. doi: 10.1016/j.amsu.2021.102477. eCollection 2021 Jul.

  PMID: 34188907 BACKGROUND

• Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther. 2009 May 1;29(9):938-46. doi: 10.1111/j.1365-2036.2009.03960.x.

  PMID: 19220208 BACKGROUND

MeSH Terms

Conditions

Peptic Ulcer Perforation

Condition Hierarchy (Ancestors)

Peptic Ulcer; Duodenal Diseases; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Stomach Diseases

Study Officials

• Doaa Hamada Abd elbaset

  Assiut University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Doaa Hamada Abd elbaset

CONTACT

01028971942; dhamada755@gmail.com

Mostafa Ahmed Hamad

CONTACT

+201222438186; mostafa_hamad@aun.edu.eg

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Model Details: Cohort

Study Record Dates

• First Submitted: September 29, 2022
• First Posted: February 8, 2023
• Study Start: May 30, 2023
• Primary Completion (Estimated): October 23, 2026
• Study Completion (Estimated): November 23, 2026
• Last Updated: March 10, 2023

Record last verified: 2023-03