NCT05674097

Brief Summary

A total of 89 patients with distal sigmoid and rectal cancer were referred for observation and underwent MS-CTA between June 2020 and March 2022. The distribution of the left colic artery (LCA) was classified, and the presence of the accessory middle colic artery (AMCA) was assessed. Blood flow paths were planned preoperatively based on the classification of LCA branches. High ligation was performed during standard radical surgery. Intraoperatively, particular care was taken to preserve the bifurcation of the ascending and descending branches of the LCA. The planned blood flow paths were then compared with the actual postoperative blood flow paths to validate the previously proposed mechanism.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
89

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 8, 2020

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 8, 2022

Completed
23 days until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2022

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

December 21, 2022

Completed
16 days until next milestone

First Posted

Study publicly available on registry

January 6, 2023

Completed
Last Updated

September 22, 2025

Status Verified

December 1, 2022

Enrollment Period

1.7 years

First QC Date

December 21, 2022

Last Update Submit

September 16, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Six pattens of blood flow and AMCA based on the preoperative observation

    1 hour after the manual subtraction computed tomography angiography (MS-CTA) procedure

Interventions

no intervention

Eligibility Criteria

Age39 Years - 81 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with distal sigmoid colon or rectal cancer and they were received routine laparoscopic surgery.

You may qualify if:

  • Clinical diagnosis of distal sigmoid colon or rectal cancer
  • cTNM stage confirmed as I-III on MRI or CT
  • Undergoing laparoscopic anterior resection (LAR)

You may not qualify if:

  • Arterial phase scanning initiated too early
  • Unclear anatomic structure on imaging
  • No postoperative enhanced CT

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Guoqin LIU

Jinan, Shandong, 250013, China

Location

MeSH Terms

Conditions

Rectal Neoplasms

Condition Hierarchy (Ancestors)

Colorectal NeoplasmsIntestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesIntestinal DiseasesRectal Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director.Liu

Study Record Dates

First Submitted

December 21, 2022

First Posted

January 6, 2023

Study Start

June 8, 2020

Primary Completion

March 8, 2022

Study Completion

March 31, 2022

Last Updated

September 22, 2025

Record last verified: 2022-12

Data Sharing

IPD Sharing
Will not share

It will be available when our paper is accepted.

Locations