Key Insights

Highlights

Success Rate

85% trial completion

Published Results

84 trials with published results (9%)

Research Maturity

366 completed trials (38% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

6.7%

65 terminated out of 974 trials

Success Rate

84.9%

-1.6% vs benchmark

Late-Stage Pipeline

8%

79 trials in Phase 3/4

Results Transparency

23%

84 of 366 completed with results

Key Signals

84 with results85% success65 terminated

Data Visualizations

Phase Distribution

708Total
Not Applicable (312)
Early P 1 (2)
P 1 (86)
P 2 (229)
P 3 (73)
P 4 (6)

Trial Status

Completed366
Unknown214
Recruiting180
Not Yet Recruiting68
Terminated65
Active Not Recruiting48

Trial Success Rate

84.9%

Benchmark: 86.5%

Based on 366 completed trials

Clinical Trials (974)

Showing 20 of 20 trials
NCT06146946Not ApplicableRecruitingPrimary

Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)

NCT03068403Not ApplicableTerminatedPrimary

Dynamic Contrast Enhanced Ultrasound for Predict and Assess Rectal Cancer Response After Neo-adjuvant Chemoradiation - RECT

NCT07736131CompletedPrimary

Learning Curve of SILS in CRC

NCT07732894Not ApplicableRecruitingPrimary

Aerobic Exercise and Guided Imagery in Low Anterior Resection Syndrome

NCT05024097Phase 2RecruitingPrimary

A Phase I-II Study to Test the Safety and Efficacy of PD1 (AB122) and Adenosine Receptor (AB928) Antagonists With Chemotherapy After Short-Course Radiation for Rectal Cancer.

NCT04098471Not ApplicableRecruitingPrimary

Total Meso-rectal Excision Versus Transanal Local Excision Followed by Radiotherapy for T2N0M0 Distal Rectal Cancer

NCT05513742Phase 2Completed

A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer

NCT05009069Phase 2Active Not Recruiting

A Study of Atezolizumab With or Without Tiragolumab Following Neoadjuvant Chemoradiotherapy in Participants With Locally Advanced Rectal Cancer

NCT07580339Phase 2Not Yet RecruitingPrimary

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

NCT04677413Phase 1Active Not RecruitingPrimary

Ultra-fractionated Radiotherapy for Rectal Cancer

NCT06577194Phase 2Active Not RecruitingPrimary

Neoadjuvant Short-Course Radiotherapy Followed by CAPOX Plus PD-1 Antibody and IL-2 in Locally Advanced Rectal Cancer (PRIDE01)

NCT07104604Phase 2RecruitingPrimary

Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal Involvement

NCT05526079Not ApplicableTerminatedPrimary

Watchful Waiting for Complete Responders to Therapy in Rectal Cancer

NCT03941366Not ApplicableTerminatedPrimary

Treatment of Adenocarcinoma of the Rectum With Transanal Local Excision for Complete Responders

NCT06904365Active Not Recruiting

Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women

NCT07711509Not ApplicableActive Not RecruitingPrimary

Autologous Fecal Microbiota Transplantation for Anal Function Recovery After Ileostomy Reversal in Rectal Cancer

NCT06340646Not ApplicableRecruiting

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

NCT06205485Phase 3RecruitingPrimary

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

NCT05538195Phase 1Completed

Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors

NCT07695519Not Yet RecruitingPrimary

SCARLET - Italian proSpeCtionAl obseRvationaL multicEntre Study on Treatment for recTal pT1 Cancer

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