Key Insights

Highlights

Success Rate

85% trial completion

Published Results

85 trials with published results (9%)

Research Maturity

366 completed trials (37% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

6.7%

66 terminated out of 985 trials

Success Rate

84.7%

-1.9% vs benchmark

Late-Stage Pipeline

8%

80 trials in Phase 3/4

Results Transparency

23%

85 of 366 completed with results

Key Signals

85 with results85% success66 terminated

Data Visualizations

Phase Distribution

717Total
Not Applicable (315)
Early P 1 (2)
P 1 (88)
P 2 (232)
P 3 (74)
P 4 (6)

Trial Status

Completed366
Unknown214
Recruiting183
Not Yet Recruiting75
Terminated66
Active Not Recruiting48

Trial Success Rate

84.7%

Benchmark: 86.6%

Based on 366 completed trials

Clinical Trials (985)

Showing 20 of 20 trials
NCT07188025Phase 3RecruitingPrimary

ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer

NCT04495088Phase 3TerminatedPrimary

Preoperative FOLFOX Versus Postoperative Risk-adapted Chemotherapy in Patients With Locally Advanced Rectal Cancer

NCT07059884Not ApplicableRecruiting

Distance-Based Exercise to Preserve Function and Prevent Disability

NCT06328361Not ApplicableRecruitingPrimary

Nordic ORgan Preservation Pilot Approach Nonrandomised Single-Arm Trial for Non-Operative Management of Rectal Cancer

NCT06565052Not ApplicableRecruitingPrimary

The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

NCT04017455Phase 2Active Not RecruitingPrimary

Neoadjuvant Treatment in Rectal Cancer With Radiotherapy Followed by Atezolizumab and Bevacizumab (TARZAN)

NCT05868226Phase 1Recruiting

PRE-ISPY Phase I/II Oncology Platform Program

NCT07847229Phase 2Not Yet RecruitingPrimary

A Prospective, Biomarker-Stratified Phase 2 Study: β-Hydroxybutyrate as a Predictive Biomarker for Short-Course Radiotherapy Followed by Chemotherapy Plus PD-1 Inhibitor Versus Chemotherapy Alone in Locally Advanced Rectal Cancer

NCT07346586Not ApplicableRecruiting

Tamsulosin for Early Catheter Removal After Rectal Cancer Surgery

NCT06958432Phase 2RecruitingPrimary

Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)

NCT03623464Not ApplicableSuspended

RCT of Mobile Apps & FitBit v. Usual Care

NCT05513742Phase 2Completed

A Study of CTX-009 in Adult Patients With Metastatic Colorectal Cancer

NCT02293954Not ApplicableActive Not Recruiting

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

NCT05752136Phase 3RecruitingPrimary

Preoperative Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Rectal Adenocarcinoma

NCT06337552Not ApplicableActive Not RecruitingPrimary

High-Fermented Food Intervention Among Locally Advanced Rectal Cancer Patients (The FEED Trial)

NCT07227636Phase 2Recruiting

A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy

NCT07132463Phase 3RecruitingPrimary

Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 Study

NCT07780305Not Yet RecruitingPrimary

ABCSG R07 Rectal Cancer Registry

NCT06246344Phase 3Active Not RecruitingPrimary

Adaptive Boost Radiotherapy to Primary Lesions and Positive Nodes in the Neoadjuvant Treatment of Locally Advanced Rectal Cancer

NCT06146946Not ApplicableRecruitingPrimary

Safety of Mid and Low Rectal Cancer Surgery Without Dissection of the No.253 Lymph Node (S-M-O-O-T-H)

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