Key Insights

Highlights

Success Rate

85% trial completion

Published Results

82 trials with published results (8%)

Research Maturity

364 completed trials (38% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

6.4%

62 terminated out of 967 trials

Success Rate

85.4%

-1.1% vs benchmark

Late-Stage Pipeline

8%

79 trials in Phase 3/4

Results Transparency

23%

82 of 364 completed with results

Key Signals

82 with results85% success62 terminated

Data Visualizations

Phase Distribution

703Total
Not Applicable (307)
Early P 1 (2)
P 1 (87)
P 2 (228)
P 3 (73)
P 4 (6)

Trial Status

Completed364
Unknown216
Recruiting179
Not Yet Recruiting68
Terminated62
Active Not Recruiting45

Trial Success Rate

85.4%

Benchmark: 86.5%

Based on 364 completed trials

Clinical Trials (967)

Showing 20 of 20 trials
NCT01148056Not ApplicableTerminatedPrimary

Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer

NCT07011576Phase 2Recruiting

A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)

NCT06051695Phase 1Recruiting

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

NCT03879109Phase 3Active Not RecruitingPrimary

Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer

NCT04804956RecruitingPrimary

Mesorectal Microbiome and Metabolome as a Prognostic Factor in Patients With Rectal Cancer

NCT06884670Phase 2CompletedPrimary

Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

NCT07188025Phase 3RecruitingPrimary

ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer

NCT07467434RecruitingPrimary

FOLFIRINOX Induction Chemotherapy for Synchronous Liver Metastases

NCT06205485Phase 3RecruitingPrimary

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

NCT07306390Not Yet Recruiting

Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)

NCT05331040WithdrawnPrimary

Radiomics in Rectal Cancer

NCT05772481RecruitingPrimary

Interest of PET-MRI in the Evaluation of the Response After Neoadjuvant Treatment of Locally Advanced Rectal Adenocarcinoma

NCT07098182Not ApplicableRecruitingPrimary

Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)

NCT07404228Not Yet RecruitingPrimary

Multidimensional Study Designed to Develop a Methodological Framework Based on MRI Data to Predict Pathological Complete Response (pCR) in Patients With Locally Advanced Rectal Cancer After Neoadjuvant Treatment

NCT06577194Phase 2RecruitingPrimary

A Single-Center, Single-Arm Study of Neoadjuvant Short-Course Radiotherapy Followed by Sequential Immunotherapy With CAPOX Combined With PD-1 Antibody and IL-2 for Locally Advanced Rectal Cancer

NCT07622017Phase 2Not Yet RecruitingPrimary

KORTUC (KRC-01) Plus Radiotherapy for Organ Preservation in Rectal Cancer

NCT05007015Not ApplicableActive Not Recruiting

Transanal Irrigation for the Management of LARS

NCT05056077Not ApplicableActive Not Recruiting

Improving Nutrition and Physical Activity for Cancer Survivors (Tools To Be Fit)

NCT07619768Not ApplicableCompletedPrimary

Self Regulation Hypnotic Intervention for Pain and Anxiety During Rectal Brachytherapy

NCT04643366Phase 2RecruitingPrimary

Total Neoadjuvant Therapy With mFOLFOX and Short-course Radiation in Resectable Rectal Cancer

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