Preoperative Frailty and Postoperative Prognosis in the Elderly After Major Surgeries
Effect of Early Identification and Prehabilitation on Postoperative Prognosis in Frail Elderly Undergoing Major Surgeries
1 other identifier
observational
189
1 country
1
Brief Summary
Elderly people often have comorbidities. However, there could be a big difference in their health status. Frailty is considered to be relevant to adverse outcomes. Some studies have found that preoperative frailty assessment and comprehensive geriatric assessment (CGA) of the elderly can improve clinical outcomes, but there has been no valid assessment established in China. Therefore it is important to design a research and help to solve this problem.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Dec 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
October 26, 2020
CompletedFirst Posted
Study publicly available on registry
December 7, 2020
CompletedStudy Start
First participant enrolled
December 20, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2022
CompletedNovember 2, 2023
May 1, 2022
1.2 years
October 26, 2020
October 31, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
the score of comprehensive complication index(CCI)
CCI is based on the complication grading by Clavien-Dindo Classification and can be calculated online (https://www.assessurgery.com).
30 days after surgery
Secondary Outcomes (1)
the incidence of postoperative pulmonary complications(PPCs)
30 days after surgery
Study Arms (2)
Frailty
patients with a FRAIL Scale of 3 to 5
Non-frailty
patients with a FRAIL Scale of 0 to 2
Interventions
Eligibility Criteria
Patients over 65 years old who are scheduled for elective major surgery under general anesthesia in Peking Union Medical College Hospital
You may qualify if:
- Aging at least 65 years old.
- Scheduled for major surgery in Peking Union Medical College Hospital .
- Understand and be willing to participate in this research, and can provide written informed consent.
You may not qualify if:
- Underwent major surgery within the last month.
- Can't complete the scale evaluation because of lower limb disability or severe knee osteoarthritis and other conditions that affect walking or climbing stairs.
- With mental or neurological disorders and unable to cooperative with investigators.
- Reject to sign the informed consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Li Xu
Peking Union Medical College Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
October 26, 2020
First Posted
December 7, 2020
Study Start
December 20, 2020
Primary Completion
February 28, 2022
Study Completion
August 30, 2022
Last Updated
November 2, 2023
Record last verified: 2022-05