Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts

NCT05650983 | Completed

• 1 other identifier: 2022LcLL-30
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this \[type of study: exercise intervention study\] is to test in describe participant health conditions. The main questions it aims to answer are:

• \[Whether physical exercise improves executive function of male heroin addicts\]
• \[Whether physical exercise improves negative thinking/affect psychological experience of male heroin addicts\] Participants will be randomly selected for medium-intensity strength training (resistance exercise,n=30), 30 will be selected for 1-hour long balloon volleyball sessions (aerobic exercise) at 60-70% volume of oxygen uptake during peak exercise, weekly 5 times for 12 weeks; and 30 will be assigned to the no-exercise control group, Participants will perform Executive function tests and the Symptom Checklist-90 Revised questionnaire at pre and post intervention. Researchers will compare resistance exercise group,aerobic exercise group and no-exercise control group to see if effects of exercise on executive function and negative thinking/affect psychological experience of male heroin addicts.

Conditions

Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease; Heroin Addicts; Executive Function; Negative Thinking/Affect

Outcome Measures

Primary Outcomes (2)

• using the Symptom Checklist-90-R (SCL-90-R) questionnaire to investigate the improvement of physical exercise on psychological symptoms in heroin addicts,

  Participants will be assessed the Symptom Checklist-90-R (SCL-90-R) questionnaire at pre and post exercise intervention.

  Month 3

• using the executive functioning tests to investigate the improvement of physical exercise on executive function in heroin addicts,

  Participants will perform executive function test

  Month 3

Study Arms (2)

1.Aerobic exercise

EXPERIMENTAL

play balloon volleyball for Aerobic exercise and aimed at maximizing the strain on the cardiovascular system (60-70% of heart rate recovery). Aerobic exercise intervention five times a week, one hour each time，for three months.

Behavioral: Aerobic exercise; Resistance exercise

2.Resistance exercise

EXPERIMENTAL

Resistance strength training for Resistance exercise and aimed at promoting the greatest hypertrophy response(65% of 1 repetition maximum and repeated up to 15 times). Resistance exercise intervention five times a week, one hour each time,for three months.

Behavioral: Aerobic exercise; Resistance exercise

Interventions

Aerobic exercise; Resistance exercise BEHAVIORAL

To investigate affect/effect of dissimilar modes of exercise, Aerobic exercise versus Resistance exercise, on execution function and psychological symptoms in heroin addicts, 1 hour of characteristic exercise protocols aiming to (a) maximize the strain on the cardiovascular system with Aerobic exercise(60-70% of heart rate recovery) and (b) promote the greatest hypertrophy response with Resistance exercise(65% of 1 repetition maximum \& repeated up to 15 time) were used. Both exercise programs were designed to match the male heroin addicts, with medium-intensity Strength-Trained for Resistance exercise and playing balloon volleyball for Aerobic exercise. Two exercise groups performed at 65% of their pre-determine peak oxygen uptake.

1.Aerobic exercise; 2.Resistance exercise

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• were men who met the Manual of Mental Disorders (DSM)-IV criteria for current heroin dependence

You may not qualify if:

• any major mental illness other than heroin addiction
• any exercise taboo

Sponsors & Collaborators

• Guangzhou Sport University: lead

Study Sites (1)

Desk and Computer and Playground

Guangzhou, Guangdongsheng, 510500, China

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 8, 2022
• First Posted: December 14, 2022
• Study Start: April 1, 2021
• Primary Completion: July 1, 2021
• Study Completion: July 1, 2021
• Last Updated: December 14, 2022

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)