NCT05314699

Brief Summary

Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, the sequence of concurrent exercise may result in different blood lactate concentration which may affect executive function. Therefore, the purposes of present study are: (1) Measuring the order effect of acute concurrent exercise on executive function. (2) Measuring whether order effect of acute concurrent exercise on executive function is mediated by blood lactate.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
99

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2021

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 15, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 29, 2021

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

February 15, 2022

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 29, 2022

Completed
8 days until next milestone

First Posted

Study publicly available on registry

April 6, 2022

Completed
Last Updated

April 6, 2022

Status Verified

March 1, 2022

Enrollment Period

6 months

First QC Date

March 29, 2022

Last Update Submit

March 29, 2022

Conditions

Keywords

acute exerciseconcurrent exerciseinhibitioncognitive flexibility

Outcome Measures

Primary Outcomes (2)

  • Stroop test

    The Stroop task consists of neutral, congruent, and incongruent trials. In neutral trials, colored rectangles were presented and participants were instructed to respond to whether the squares were red, blue, or green. For congruent and incongruent trials, participants were presented with the names of the three Chinese color words of 紅 (red), 藍 (blue), or 綠 (green) printed in either the same (congruent) or different (incongruent) ink color and instructed to respond to the color of the ink while inhibiting the meaning of the word.

    30 minutes

  • task switch test

    The shifting aspect of executive function was assessed by means of a computer version of the task-switching test. In brief, each participant was presented with six blocks of 64 trials. For the first block, the participant was required to identify whether the stimulus (i.e., digits 1-9, without digit 5) within the solid-line square was greater/less than the digit 5. For the second block, the participant identified whether the stimulus within the dotted-line square was even/odd. The blocks 3-6 consisted of an equal number of stimuli from the first and second blocks forming an alternating-runs paradigm.

    30 minutes

Other Outcomes (1)

  • blood lactate

    1 minutes

Study Arms (3)

resistance-aerobic exercise group, RA

EXPERIMENTAL

Participants conduct 5-min warm up, 13-min resistance exercise, 12-min aerobic exercise, and 5-min cool down.

Behavioral: resistance-aerobic exercise, RA

aerobic-resistance exercise group, AR

EXPERIMENTAL

Participants conduct 5-min warm up, 12-min aerobic exercise, 13-min resistance exercise, and 5-min cool down.

Behavioral: aerobic-resistance exercise, AR

reading control group, RC

NO INTERVENTION

Participants conduct reading for 35 minutes.

Interventions

Participants conduct 5-min warm up, 13-min resistance exercise, 12-min aerobic exercise, and 5-min cool down.

resistance-aerobic exercise group, RA

Participants conduct warm up for 5-min, aerobic exercise for 12-min, resistance exercise for 13-min, and 5-min cold down.

aerobic-resistance exercise group, AR

Eligibility Criteria

Age21 Years - 28 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • no history of psychiatric or neurological disorders
  • no history of cardiovascular disease
  • normal or corrected to normal vision and normal color perception
  • right handed
  • \< BMI \< 27

You may not qualify if:

  • \. Diagnosed with epilepsy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Physical Education and Sport Sciences, National Taiwan Normal University

Taipei, 106, Taiwan

Location

MeSH Terms

Conditions

Inhibition, Psychological

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • Yu-Kai Chang, Ph.D.

    Department of Physical Education and Sport Sciences, National Taiwan Normal University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Participants were randomly assigned to three group, namely the resistance-aerobic exercise group (RA), the aerobic-resistance exercise group (AR), and the reading control group (RC). Participants in RA groups were asked to finish 5 min warm-up, 13 min resistance exercise, 12 min aerobic exercise, and 5 min cool down. Participants in AR groups were asked to finish 5 min warm-up, 12 min aerobic exercise, 13 min resistance exercise, and 5 min cool down. Participants in RC group were required to finish 35 min reading. All groups took a 30 min cognitive test before and after the intervention.The blood lactate were collected before, 17 minutes after, and after the intervention.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 29, 2022

First Posted

April 6, 2022

Study Start

June 15, 2021

Primary Completion

November 29, 2021

Study Completion

February 15, 2022

Last Updated

April 6, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will not share

Locations