The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study

NCT05314634 | Completed Results DMC

• 1 other identifier: PACNL_rueihongli_CE
• Study Type: interventional
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

Executive function is a high-level cognition which plays an important role in our life. Meta-analysis study has demonstrated that acute exercise could improve executive function. However, it is still unclear whether executive function can be enhanced by the concurrent exercise that combines aerobic and resistance exercise. Moreover, previous studies indicated that acute exercise could increase the concentration of blood lactate which is positive correlated to executive function. It is still unclear whether the effect of acute concurrent exercise on executive function is mediated by blood lactate. Therefore, the purposes of present study are: (1) Measuring the effect of acute concurrent exercise and aerobic exercise on executive function. (2) Measuring whether the effect of acute concurrent exercise on executive function is mediated by blood lactate.

Conditions

Executive Function

Keywords

acute exercise; concurrent exercise; cognitive flexibility

Outcome Measures

Primary Outcomes (1)

• Task Switch Test Response Times

  The shifting aspect of executive function was assessed using a computerised task-switching test. Each participant (N=78) completed 384 trials across six blocks (64 trials per block). The test consisted of two types of cognitive tasks: (1) number magnitude judgment (greater/less than 5) for digits 1-9 presented in solid-line squares, and (2) odd/even judgment for numbers presented in dotted-line squares. Performance was analysed by calculating each participant's mean response time (milliseconds) under four conditions: Homogeneous condition: Blocks where participants performed the same task repeatedly (Blocks 1 \& 2, e.g., AAAA or BBBB) Heterogeneous condition: Blocks where tasks were mixed (Blocks 3-6, e.g., AABBAA) Non-switch trials: Consecutive trials of the same task type within heterogeneous blocks (e.g., AA or BB) Switch trials: Trials where the task changed from the previous trial within heterogeneous blocks (e.g., AB or BA) Lower response time represents better task perform

  30 minutes

Other Outcomes (2)

• Blood Lactate

  before intervention, 17 minutes after intervention, and immediately after the 35 minute intervention

• Stroop Task

  30 minutes

Study Arms (3)

concurrent exercise group, CE

EXPERIMENTAL

Participants conduct 5-min warm up, 12-min aerobic exercise, 13-min resistance exercise, and 5-min cool down.

Behavioral: concurrent exercise

aerobic exercise group, AE

EXPERIMENTAL

Participants conduct 5-min warm up, 25-min aerobic exercise, and 5-min cool down.

Behavioral: aerobic exercise

reading control group, RC

NO INTERVENTION

Participants conduct reading for 35 minutes.

Interventions

concurrent exercise BEHAVIORAL

Participants conduct warm up for 5-min, aerobic exercise for 12-min, resistance exercise for 13-min, and 5-min cool down.

concurrent exercise group, CE

aerobic exercise BEHAVIORAL

Participants conduct warm up for 5-min, resistance training for 25-min, and 5-min cool down.

aerobic exercise group, AE

Eligibility Criteria

• Age: 21 Years - 28 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• no history of psychiatric or neurological disorders
• no history of cardiovascular disease
• normal or corrected to normal vision and normal color perception
• right handed
• \< BMI \< 27

You may not qualify if:

• \. Diagnosed with epilepsy

Sponsors & Collaborators

• National Taiwan Normal University: lead

Study Sites (1)

Department of Physical Education and Sport Sciences, National Taiwan Normal University

Taipei, 106, Taiwan

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Results Point of Contact

• Title: Ruei-Hong Li
• Organization: National Taiwan Normal University

rueihongli@gmail.com

+886988163220

Study Officials

• Yu-Kai Chang, Ph.D.

  Department of Physical Education and Sport Sciences, National Taiwan Normal University

  STUDY DIRECTOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Participants were randomly assigned to three group, namely the concurrent exercise group (CE), the aerobic exercise group (AE), and the reading control group (RC). Participants in CE groups were asked to finish 5 min warm-up, 12 min aerobic exercise, 13 min resistance exercise, and 5 min cool down. Participants in the AE group were asked to finish 5 min warm-up, 25 min aerobic exercise, and 5 min cool down. Participants in RC group were required to finish 35 min reading. All groups took a 30 min cognitive test before and after the intervention. The blood lactate were collected before, 17 minutes after, and after the intervention.

Study Record Dates

• First Submitted: March 29, 2022
• First Posted: April 6, 2022
• Study Start: February 15, 2021
• Primary Completion: August 15, 2021
• Study Completion: February 15, 2022
• Last Updated: February 20, 2025
• Results First Posted: February 20, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)