Pregnancy Rate in Direct Versus Afterload Technique of Embryo Transfer
Pregnancy Rate in Single Step Versus After Load Technique of Embryo Transfer: a Retrospective Analysis
1 other identifier
observational
8,127
0 countries
N/A
Brief Summary
The primary outcome of the study is to determine if a difference in terms of pregnancy rate exists between direct and afterload embryo transfer (ET) techniques. The secondary end points include the evaluation of the difficult transfer rates.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2016
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2021
CompletedFirst Submitted
Initial submission to the registry
May 3, 2022
CompletedFirst Posted
Study publicly available on registry
May 6, 2022
CompletedMay 24, 2022
May 1, 2022
6 years
May 3, 2022
May 17, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
clinical pregnancy rate
number of pregnancies diagnosed by ultrasonographic visualization of one or more gestational sacs x 100 divided by the number of embryo transfer cycles
6 years
Secondary Outcomes (1)
difficult transfer rate
6 years
Study Arms (2)
clinical pregnancies with direct catheter
Clinical pregnancies occurred after fresh and frozen blastocyst transfers using direct technique.
clinical pregnancies with afterload catheter
Clinical pregnancies occurred after fresh and frozen blastocyst transfers using afterload technique.
Eligibility Criteria
The study database includes all the single fresh and frozen (G5-G6) blastocyst transfers performed at Humanitas Fertility Centre between 1st January 2016 and 31th December 2021 by using the direct and afterload protocols.
You may qualify if:
- IVF procedure
- Fresh and frozen single blastocyst transfer
You may not qualify if:
- Any blastocysts that underwent PGS testing
- Embryos derived from gamete donation
- Embryos imported from other centers
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Cirillo F, Immediata V, Ronchetti C, Carletti T, Morenghi E, Albani E, Baggiani A, Levi-Setti PE. Steps forward in embryo transfer technique: a retrospective study comparing direct versus afterload catheters at different time frames. J Assist Reprod Genet. 2023 Dec;40(12):2895-2902. doi: 10.1007/s10815-023-02957-y. Epub 2023 Oct 11.
PMID: 37819552DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
May 3, 2022
First Posted
May 6, 2022
Study Start
January 1, 2016
Primary Completion
December 31, 2021
Study Completion
December 31, 2021
Last Updated
May 24, 2022
Record last verified: 2022-05