Technical Factors of Embryo Transfer Procedure That Might Affect the Outcome

NCT04408547 | Completed

• 1 other identifier: IakentroFC
• Study Type: observational
• Target: 3,512
• Locations: 1 country
• Sites: 1

Brief Summary

Analysis our Embryo transfer data, prospectively collected during the last 6 years (2014- 2019), performed by the same operator YP, who has been doing embryo transfers since 1984. All factors that might impact the embryo transfer will be analyzed. We want to see which factors that influence the success rate are not related to the subjectivity of the operator and could be adjusted through different approaches.

Conditions

IVF; Pregnancy

Outcome Measures

Primary Outcomes (3)

• Number of patients with bhCG positive test after embryo transfer

  Number of patients bhCG positive up to12 days after embryo transfer

  Number of patients bhCG positive up to12 days after embryo transfer

• Number of patients with on going clinical pregnancy

  Number of patients with on going clinical pregnancy up to12 weeks after embryo transfer

  Number of patients with on going clinical pregnancy up to 12 weeks after embryo transfer

• Number of live births after embryo transfer

  Number oflive birth up to9 months after embryo transfer

  Number oflive birth up to 9 months after embryo transfer

Secondary Outcomes (6)

• Percentage of fullnes of bladder

  At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer

• Endometrial thickness

  prior to embryo transfer

• Uterine axe orientation

  At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer

• Type of embryo transfer catheter

  At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer

• Distance from the fundus of the embryo release

  At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer

Study Arms (2)

soft catheter

Patients who underwent embryo transfer with a soft catheter

Device: embryo transfer catheter

stiff catheter

Patients who underwent embryo transfer with a stiff catheter because soft couldn't pass

Device: embryo transfer catheter

Interventions

embryo transfer catheter DEVICE

undergoing embryo transfer

soft catheter; stiff catheter

Eligibility Criteria

• Age: 18 Years - 49 Years
• Gender Eligibility Details: Only women can undergo embryo transfer
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Women undergoing embryo transfer after IVF

You may qualify if:

• Women undergoing embryo transfer after IVF

You may not qualify if:

• Women with known embryo implantation issues

Sponsors & Collaborators

• Iakentro Fertility Centre: lead

Study Sites (1)

IAKENTRO Fertility Center

Thessaloniki, 542 50, Greece

Location

Related Publications (1)

• Prapas N, Prapas Y, Panagiotidis Y, Prapa S, Vanderzwalmen P, Makedos G. Cervical dilatation has a positive impact on the outcome of IVF in randomly assigned cases having two previous difficult embryo transfers. Hum Reprod. 2004 Aug;19(8):1791-5. doi: 10.1093/humrep/deh320. Epub 2004 Jun 3.

  PMID: 15178658 RESULT

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Obstetrics - Gynaecology

Study Record Dates

• First Submitted: May 13, 2020
• First Posted: May 29, 2020
• Study Start: January 3, 2014
• Primary Completion: December 30, 2019
• Study Completion: December 30, 2019
• Last Updated: June 4, 2020

Record last verified: 2020-05

Data Sharing

• IPD Sharing: Will not share

Locations

GR (1)