NCT05329714

Brief Summary

PVRI-GoDeep is a PH Meta-Registry, run under the umbrella of the Pulmonary Vascular Research Institute (PVRI). It merges anonymized PH patient related data from various local registries around the world run under the responsibility of PVRI members. It will be operated under the auspices of the University of Giessen/Giessen PH center. Combining deep phenotyping with worldwide outreach, PVRI-GoDeep aims to offer insights into specific geographical and ethnical profiles of PH, to deepen the epidemiological, clinical and molecular understanding of this disease and to promote strategies for improved individualized treatment of PH patients.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40,000

participants targeted

Target at P75+ for all trials

Timeline
350mo left

Started Jan 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress18%
Jan 2020Jan 2055

Study Start

First participant enrolled

January 30, 2020

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

March 14, 2022

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 15, 2022

Completed
27.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2050

Expected
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2055

Last Updated

April 4, 2025

Status Verified

April 1, 2025

Enrollment Period

30 years

First QC Date

March 14, 2022

Last Update Submit

April 1, 2025

Conditions

Keywords

Pulmonary HypertensionData IntegrationStandardizationGlobal HealthQuality Indicators

Outcome Measures

Primary Outcomes (1)

  • Global analysis of PH patients

    Global comparison and analysis of the course of disease of PH patients

    From entry into the registry up to 10 years

Study Arms (2)

Patients with Pulmonary Hypertension

Patients with a diagnosis of pulmonary hypertension typically diagnosed via right heart catheterization.

Control Group

Participating PH centers can optionally provide data about patients with exclusion of pulmonary hypertension

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Global cohort of patients with pulmonary hypertension (PH)

You may qualify if:

  • Clinical Diagnosis of Pulmonary Hypertension

You may not qualify if:

  • none

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Giessen PH Center

Giessen, Hesse, 35392, Germany

RECRUITING

Related Publications (1)

  • Yogeswaran A, Gall H, Funderich M, Wilkins MR, Howard L, Kiely DG, Lawrie A, Hassoun PM, Sirenklo Y, Torbas O, Sweatt AJ, Zamanian RT, Williams PG, Frauendorf M, Arvanitaki A, Giannakoulas G, Saleh K, Sabbour H, Cajigas HR, Frantz R, Al Ghouleh I, Chan SY, Brittain E, Annis JS, Pepe A, Ghio S, Orfanos S, Anthi A, Majeed RW, Wilhelm J, Ghofrani HA, Richter MJ, Grimminger F, Sahay S, Tello K, Seeger W; Pulmonary Vascular Research Institute GoDeep Consortium. Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension: A Pulmonary Vascular Research Institute GoDeep Meta-Registry Analysis. Chest. 2024 Sep;166(3):585-603. doi: 10.1016/j.chest.2024.03.018. Epub 2024 Mar 19.

MeSH Terms

Conditions

Hypertension, Pulmonary

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesHypertensionVascular DiseasesCardiovascular Diseases

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 14, 2022

First Posted

April 15, 2022

Study Start

January 30, 2020

Primary Completion (Estimated)

January 30, 2050

Study Completion (Estimated)

January 30, 2055

Last Updated

April 4, 2025

Record last verified: 2025-04

Locations