Key Insights

Highlights

Success Rate

82% trial completion

Published Results

92 trials with published results (14%)

Research Maturity

300 completed trials (46% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.3%

67 terminated out of 650 trials

Success Rate

81.7%

-4.8% vs benchmark

Late-Stage Pipeline

14%

94 trials in Phase 3/4

Results Transparency

31%

92 of 300 completed with results

Key Signals

92 with results82% success67 terminated

Data Visualizations

Phase Distribution

389Total
Not Applicable (149)
Early P 1 (7)
P 1 (46)
P 2 (93)
P 3 (60)
P 4 (34)

Trial Status

Completed300
Recruiting96
Unknown93
Terminated67
Withdrawn34
Not Yet Recruiting33

Trial Success Rate

81.7%

Benchmark: 86.5%

Based on 300 completed trials

Clinical Trials (650)

Showing 20 of 20 trials
NCT07647549Not Yet RecruitingPrimary

Pulmonary Hypertension (PH) Biorepository for Translational Research

NCT06770023Phase 1Recruiting

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

NCT07561034Not ApplicableRecruitingPrimary

The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease

NCT05983250Phase 3Active Not RecruitingPrimary

LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF

NCT06336798Phase 2RecruitingPrimary

Bioenergetic Effect of Pioglitazone in CLD-PH

NCT05824923Phase 3Active Not RecruitingPrimary

A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure

NCT01730092Recruiting

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT00011648CompletedPrimary

Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia

NCT07694713Not Yet Recruiting

Dynamic Changes in Right Ventricle and Pulmonary Artery Coupling Among COPD Patients With Acute Exacerbation

NCT06616974Phase 2Active Not RecruitingPrimary

A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)

NCT07214376Not ApplicableRecruitingPrimary

A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

NCT07132788Not ApplicableRecruitingPrimary

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

NCT04084678Phase 3TerminatedPrimary

Study of Ralinepag on Exercise Capacity by Cardiopulmonary Exercise Testing (CPET) in WHO Group 1 PH Subjects

NCT06911632Not ApplicableRecruitingPrimary

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

NCT00678821Phase 2CompletedPrimary

Aerobic Exercise in Patients With Pulmonary Hypertension

NCT06038149Active Not RecruitingPrimary

Improving Pulmonary Hypertension Screening by Echocardiography

NCT03629340Phase 2CompletedPrimary

Metformin for Pulmonary Hypertension HFpEF

NCT07556185Not ApplicableRecruiting

MedlyPeds Feasibility Study

NCT06129240RecruitingPrimary

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

NCT07667673RecruitingPrimary

Multimodality RV Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 PAH

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