Pulmonary Hypertension
635
93
111
294
Key Insights
Highlights
Success Rate
82% trial completion
Published Results
91 trials with published results (14%)
Research Maturity
294 completed trials (46% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 62/100
10.4%
66 terminated out of 635 trials
81.7%
-4.8% vs benchmark
15%
94 trials in Phase 3/4
31%
91 of 294 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 294 completed trials
Clinical Trials (635)
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension
A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489
Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD
Aerobic Exercise in Patients With Pulmonary Hypertension
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
Insights Into Pediatric Pulmonary Hypertension: A Real-World Registry of Epidemiology and Outcomes
A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study)
Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants
Reverse Remodeling of the Pulmonary Vasculature: a Longitudinal, Investigational Study of the Effects of Sotatercept.
Portosystemic Shunt-associated Pulmonary Hypertension Multi-center Prospective Cohort Study
Development of Novel Physiological CMR Methods in Health and Disease
Trans-pulmonary Biomarkers in Pulmonary Hypertension
Heart Institute Biobank & Registry for Adult Congenital Heart Disease and Related Disorders
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease