Key Insights

Highlights

Success Rate

82% trial completion

Published Results

91 trials with published results (14%)

Research Maturity

299 completed trials (47% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

10.4%

67 terminated out of 643 trials

Success Rate

81.7%

-4.8% vs benchmark

Late-Stage Pipeline

15%

94 trials in Phase 3/4

Results Transparency

30%

91 of 299 completed with results

Key Signals

91 with results82% success67 terminated

Data Visualizations

Phase Distribution

388Total
Not Applicable (149)
Early P 1 (6)
P 1 (46)
P 2 (93)
P 3 (60)
P 4 (34)

Trial Status

Completed299
Unknown93
Recruiting93
Terminated67
Withdrawn34
Not Yet Recruiting32

Trial Success Rate

81.7%

Benchmark: 86.5%

Based on 299 completed trials

Clinical Trials (643)

Showing 20 of 20 trials
NCT01730092Recruiting

Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

NCT07641400Not Yet Recruiting

Pulmonary Artery Pressure in Predicting Pulmonary Embolism in Patients Presenting To The Emergency Department With Dyspnea

NCT06388421Recruiting

DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

NCT06526195Not ApplicableRecruiting

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

NCT00011648CompletedPrimary

Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia

NCT07614438Phase 2Not Yet Recruiting

Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery,

NCT03022851Not ApplicableCompletedPrimary

The Prophet Trial -Pilot Study to Assess Safety and Efficacy of a Novel Atrial Flow Regulator (AFR) in Patients With Pulmonary Hypertension

NCT07613216Not Yet Recruiting

A Comparison of a Medication Adherence Platform (FORTISKAP™) vs. Usual Care in Subjects on Oral Medications for the Treatment of Interstitial Lung Disease, Sarcoid and Pulmonary Hypertension

NCT03901287Not ApplicableCompletedPrimary

Quantitative Dual Energy Computed Tomography in Pulmonary Hypertension

NCT05776225Completed

Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection

NCT03794583Phase 3TerminatedPrimary

Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)

NCT07179380Phase 3RecruitingPrimary

Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

NCT07234032Phase 3Not Yet RecruitingPrimary

An Open-Label Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

NCT00678821Phase 2CompletedPrimary

Aerobic Exercise in Patients With Pulmonary Hypertension

NCT07073820Phase 2RecruitingPrimary

A Study to Learn About the Study Medicine (Called PF-07868489) in People With Pulmonary Arterial Hypertension Who Have Previously Participated in a Clinical Study With PF-07868489

NCT05937854Phase 2Recruiting

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

NCT07206173CompletedPrimary

Londrina Activities of Daily Living Protocol in Pulmonary Hypertension

NCT07132788Not ApplicableRecruitingPrimary

Understanding the Effects of Pulmonary Arterial Hypertension on Lean Muscle Mass

NCT07576894Not ApplicableRecruiting

Right Ventricular Response to Exercise Among Patients With Chronic Obstructive Pulmonary Disease

NCT05896579Not ApplicableRecruiting

Phenotyping Resting and Exertional Right Ventricular Dysfunction Among Patients With Chronic Obstructive Pulmonary Disease

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