NCT04145024

Brief Summary

Giessen Pulmonary Hypertension Registry and Biobank

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10,000

participants targeted

Target at P75+ for all trials

Timeline
115mo left

Started Jul 1993

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress78%
Jul 1993Jan 2036

Study Start

First participant enrolled

July 1, 1993

Completed
26.3 years until next milestone

First Submitted

Initial submission to the registry

October 28, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 30, 2019

Completed
15.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 15, 2035

Expected
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 15, 2036

Last Updated

December 11, 2024

Status Verified

December 1, 2024

Enrollment Period

42.1 years

First QC Date

October 28, 2019

Last Update Submit

December 10, 2024

Conditions

Pulmonary Hypertension

Outcome Measures

Primary Outcomes (1)

  • Survival

    Transplant-free survival of PH patients

    Up to 20 years after enrollment

Study Arms (6)

Pulmonary arterial hypertension

Group 1 PH

Pulmonary hypertension due to left heart disease

Group 2 PH

Pulmonary hypertension due to lung disease

Group 3 PH

Chronic thromboembolic pulmonary hypertension

Group 4 PH

Miscellaneous

Group 5 PH

Exclusion PH

Patient with invasively excluded PH

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Study population includes patients referred to our tertial PH expert center in Giessen with suspected PH.

You may qualify if:

  • Right heart catheterization for PH diagnosis in Giessen

You may not qualify if:

  • informed consent missing

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Intermal Medicine - Universities of Giessen and Marburg Lung Center

Giessen, 35392, Germany

RECRUITING

Related Publications (1)

  • Gall H, Felix JF, Schneck FK, Milger K, Sommer N, Voswinckel R, Franco OH, Hofman A, Schermuly RT, Weissmann N, Grimminger F, Seeger W, Ghofrani HA. The Giessen Pulmonary Hypertension Registry: Survival in pulmonary hypertension subgroups. J Heart Lung Transplant. 2017 Sep;36(9):957-967. doi: 10.1016/j.healun.2017.02.016. Epub 2017 Feb 17.

    PMID: 28302503RESULT

MeSH Terms

Conditions

Hypertension, Pulmonary

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesHypertensionVascular DiseasesCardiovascular Diseases

Study Officials

  • Khodr Tello, MD

    University Clinics of Giessen and Marburg

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Khodr Tello, MD

CONTACT

0641/985-51250khodr.tello@innere.med.uni-giessen.de

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
20 Years
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 28, 2019

First Posted

October 30, 2019

Study Start

July 1, 1993

Primary Completion (Estimated)

July 15, 2035

Study Completion (Estimated)

January 15, 2036

Last Updated

December 11, 2024

Record last verified: 2024-12

Locations

DE(1)