Integrated Cognitive Behavioral Treatment for Substance Use and Depressive Symptoms: a Homeless Case Series

NCT05329181 | Completed

• 1 other identifier: INTER
• Study Type: interventional
• Target: 4
• Locations: 0 countries
• Sites: N/A

Brief Summary

This case series and feasibility trial evaluated a novel integrated cognitive behavioral treatment, which was adapted specifically for homeless individuals and developed to treat substance use and depressive symptoms simultaneously. The integrated cognitive behavioral treatment was delivered among four homeless individuals enrolled in the Treatment First program (a social services program where treatment is offered in conjunction with temporary transitional housing), who had access to stable and sober housing milieus.

Conditions

Cognitive Behavioral Therapy

Outcome Measures

Primary Outcomes (1)

• The TimeLine Follow Back

  The TimeLine Follow Back, a retrospective calendar instrument to assess days and quantity of alcohol and drug use, was used as primary measure for substance use. The TimeLine Follow Back have been found to have good psychometric properties in a homeless population (Sacks et al., 2003). Number of units (alcohol or drug use) per week were reported as means per week, during baseline and treatment. The TimeLine Follow Back was not administered at follow up.

  A retrospective 90-day TimeLine Follow Back interview at baseline, and a retrospective 7 days TimeLine Follow Back self-report measure assessed weekly during treatment sessions (up to 15 sessions/weeks).

Secondary Outcomes (8)

• The Patient Health Questionnaire

  1 week

• The Generalized Anxiety Questionnaire

  2 weeks

• The Alcohol Use Disorders Identification Test

  1 year

• The Drug Use Disorders Identification Test

  1 year

• Housing status

  1 day

Study Arms (1)

Integrated cognitive behavioral therapy adapted for homeless individuals

OTHER

Four homeless individuals enrolled in the Treatment First program (a social services program where treatment is offered in conjunction with temporary transitional housing), who had access to stable and sober housing milieus, received the integrated cognitive behavioral treatment.

Behavioral: Integrated cognitive behavioral treatment

Interventions

Integrated cognitive behavioral treatment BEHAVIORAL

Integrated cognitive behavioral treatment adapted specifically for homeless individuals and developed to treat substance use and depressive symptoms simultaneously

Integrated cognitive behavioral therapy adapted for homeless individuals

Eligibility Criteria

• Age: 16 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• Fulfilled the Diagnostic and Statistical Manual of Mental Disorders criteria for Alcohol Use Disorder or Substance Use Disorder
• Fulfilled the Swedish criteria for homelessness and had access to "steady housing" (defined as situation 3 or 4 according to Sun et al. \[2012\])
• Were between 16-65 years old
• Were able to read and write Swedish and were able to carry out treatment, 5-15 sessions together with homework assignments
• Had regular contact with a social worker at the social welfare office for the homeless.

You may not qualify if:

• Another primary psychiatric condition (e.g., bipolar disorder, psychosis, suicidal ideation)
• Failure to attend first two treatment sessions
• Other aggravating circumstances, for example violence in close relationships.

Sponsors & Collaborators

• Karolinska Institutet: lead
• Ersta Diakoni: collaborator

Related Publications (1)

• Molander O, Bjureberg J, Sahlin H, Beijer U, Hellner C, Ljotsson B. Integrated cognitive behavioral treatment for substance use and depressive symptoms: a homeless case series and feasibility study. Pilot Feasibility Stud. 2023 May 5;9(1):76. doi: 10.1186/s40814-023-01305-2.

  PMID: 37147667 DERIVED

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: March 21, 2022
• First Posted: April 14, 2022
• Study Start: June 1, 2016
• Primary Completion: January 31, 2017
• Study Completion: January 31, 2017
• Last Updated: April 14, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share