Brief Culturally Adapted CBT for OCD

NCT07232823 | Recruiting DMC

• 1 other identifier: CaCBTOCD24
• Study Type: interventional
• Target: 166
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose aims to assess the efficacy of Brief Culturally Adapted Cognitive Behaviour Therapy (Ca-CBT) for the treatment of Obsessive Compulsive Disorder (OCD).

Conditions

Obsessive-Compulsive Disorder; Cognitive Behavioral Therapy

Keywords

CBT; CaCBT; OCD

Outcome Measures

Primary Outcomes (2)

• Efficacy of brief culturally adapted cognitive behaviour therapy (CaCBT) for OCD

  By comparing pre- and post-treatment OCD scores measured through the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS).

  6 weeks

• Acceptability of the brief culturally adapted cognitive behaviour therapy (CaCBT) for OCD

  Feedback will be taken from both patients and their family members, who will be trained as co-therapists, to evaluate their satisfaction with the therapy.

  6 weeks

Secondary Outcomes (2)

• Reduction in depression and anxiety associated with OCD

  6 weeks

• Reduction in functioning decline associated with OCD

  6 weeks

Study Arms (2)

Brief culturally adapted CBT (CaCBT) group

EXPERIMENTAL

Participants in this group will receive the Culturally Adapted CBT (CaCBT) manual along with treatment as usual (which typically involves medication prescriptions and regular hospital visits). The manual will focus on psychoeducation, symptom management, Exposure and Response prevention (ERP), thought distraction techniques, relaxation exercises, detection of mood and thoughts, cognitive errors, changing negative thinking, behavioural activation, problem solving, improving relationships and communication skills, Thought diaries and progress diary.

Other: Brief culturally adapted cognitive behaviour therapy (CaCBT)

Treatment as usual group

NO INTERVENTION

Participants in this group will receive only treatment as usual (TAU), which typically involves medication prescriptions and regular hospital visits. Research psychologists delivering the intervention will not be involved with participants allocated to TAU.

Interventions

Brief culturally adapted cognitive behaviour therapy (CaCBT) OTHER

The intervention will focus on psychoeducation, symptom management, Exposure and Response prevention (ERP), thought distraction techniques, relaxation exercises, detection of mood and thoughts, cognitive errors, changing negative thinking, behavioural activation, problem solving, improving relationships and communication skills, Thought diaries and progress diary.

Brief culturally adapted CBT (CaCBT) group

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Participants aged 18 years or above
• Participants with at least an elementary level of reading and writing
• Clinical diagnosis of Obsessive Compulsive Disorder, either alone or comorbid with depression or anxiety

You may not qualify if:

• Participants with excessive use of alcohol or drugs (using ICD-10 RDC for alcohol or drug abuse or dependence)
• Those with significant cognitive impairment (for example, intellectual disability or dementia)
• Or those with OCD comorbid active psychosis

Sponsors & Collaborators

• Pakistan Association of Cognitive Therapists: lead

Study Sites (1)

Professional Association of Cognitive Therapy

Lahore, Punjab Province, 54000, Pakistan

RECRUITING

MeSH Terms

Conditions

Obsessive-Compulsive Disorder

Condition Hierarchy (Ancestors)

Anxiety Disorders; Mental Disorders

Study Officials

• Farooq Naeem

  Professional Association of Cognitive Therapy

  PRINCIPAL INVESTIGATOR

• Muhammad Aslam

  Professional Association of Cognitive Therapy

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Muhammad Aslam

CONTACT

+92 301 7170139; Muhammadaslam139@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: This will be a randomised, controlled, assessor-blind clinical trial. It will be carried out at Recovery Psychiatric \& Addiction Treatment, Rehab \& Psychotherapy Centre, Lahore, and Dr Muhammad Afzal Khan Clinic, Faisalabad. The participants will be provided with oral and written information about the study, and written informed consent will be obtained. Participants who agree to participate will be allocated to one of the groups: brief CaCBT plus TAU (Treatment group) or TAU alone (Control group).

Study Record Dates

• First Submitted: October 16, 2024
• First Posted: November 18, 2025
• Study Start: October 20, 2024
• Primary Completion: December 10, 2025
• Study Completion: December 31, 2025
• Last Updated: November 18, 2025

Record last verified: 2025-11

Locations

PA (1)