NCT05113875

Brief Summary

The aim of this study is to describe the patient clinical profile, resource requirements, and health system dynamics in a field hospital during the second wave of the Coronavirus (COVID-19) pandemic, leading to the outbreak of viral severe acute respiratory syndrome (SARS-CoV-2 virus), in South Africa. By describing the field hospital in this unique setting, the investigators hope to provide an efficient guide to similar settings across low- and middle-income countries. This was a retrospective, single-center study. A total of 596 patients with confirmed COVID-19 were admitted to Mitchells Plain Hospital of Hope (MPHOH), Cape Town, South Africa, between January 1st and February 28th, 2021. Patient clinical characteristics, outcome, and resource allocation was collected. Daily hospital dynamics, including admissions, discharges, deaths and oxygen use was analyzed and compared to the local and national COVID-19 incidence rates.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
596

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 11, 2021

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2021

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

November 3, 2021

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 9, 2021

Completed
Last Updated

November 9, 2021

Status Verified

November 1, 2021

Enrollment Period

2 months

First QC Date

November 3, 2021

Last Update Submit

November 7, 2021

Conditions

Outcome Measures

Primary Outcomes (27)

  • Patient Demographics

    Patient age (in numbers)

    January 1st to February 29th 2021

  • Patient Demographics

    Patient sex (male or female)

    January 1st to February 29th 2021

  • Patient Clinical Condition

    Patient medical comorbidities on admission (categorical)

    January 1st to February 29th 2021

  • Patient Clinical Condition

    If patient diabetic, type of diabetic treatment received in hospital (oral vs insulin therapy)

    January 1st to February 29th 2021

  • Patient Clinical Condition

    If patient diabetic, glycated haemoglobin (HBA1C) level during admission (in numbers)

    January 1st to February 29th 2021

  • Patient Clinical Condition

    Patient clinical complications during hospital admission (categorical)

    January 1st to February 29th 2021

  • Patient Clinical Condition

    If patient received antibiotic treatment during admission, name of infection treated (categorical)

    January 1st to February 29th 2021

  • Patient Clinical condition

    Patient ICU priority triage score on admission (in numbers)

    January 1st to February 29th 2021

  • Hospital Human Resources Utilized

    Number of patients who utilized palliative care services (in numbers)

    January 1st to February 29th 2021

  • Hospital Human Resources Utilized

    Number of patients who utilized dietician services (in numbers)

    January 1st to February 29th 2021

  • Hospital Human Resources Utilized

    Number of patients who utilized physiotherapy services (in numbers)

    January 1st to February 29th 2021

  • Hospital Physical Resources Utilized

    Number of patients requiring oxygen therapy during admission (in numbers)

    January 1st to February 29th 2021

  • Hospital Physical Resources Utilized

    Type of oxygen therapy utilized by each patient (Categorical: nasal prong oxygen; face mask oxygen; or high flow oxygen)

    January 1st to February 29th 2021

  • Hospital Physical Resources Utilized

    Duration of oxygen therapy for each patient (in days)

    January 1st to February 29th 2021

  • Hospital Physical Resources Utilized

    Number of patients requiring antibiotic treatment (in numbers)

    January 1st to February 29th 2021

  • Hospital Physical Resources Utilized

    If patient required antibiotic therapy, name of antibiotic given (categorical)

    January 1st to February 29th 2021

  • Hospital Physical resources Utilized

    Patient duration of hospital stay (in days)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily number of patients admitted to hospital (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily number of inpatients at hospital (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily number of patients discharged from hospital (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily number of patient deaths (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily number of patients transferred out of hospital to another medical facility (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily hospital bed capacity (in numbers/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Daily hospital oxygen consumption (in kg/day)

    January 1st to February 29th 2021

  • Health System Dynamics

    Name of hospital from which each patient was referred from (categorical)

    January 1st to February 29th 2021

  • Local Incidence rates of COVID-19 infections

    South African National COVID-19 incidence rates per week (in numbers/week)

    December 1st 2020 to February 29th 2021

  • Local Incidence rates of COVID-19 infections

    Western Cape Provincial COVID-19 incidence rates per week (in numbers/week)

    December 1st 2020 to February 29th 2021

Study Arms (1)

COVID-19 Patients

Completed Sample of all patients admitted to the Mitchells Plain Hospital of Hope COVID-19 Field Hospital between January 1st and February 29th 2021. All patients were diagnosed with COVID-19 prior to admission to the hospital and were transferred directly from a referring hospital.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population is from an underserved community utilizing public health services. The population in based in Mitchells Plain, Cape Town South Africa.

You may qualify if:

  • All patients admitted to the Mitchells Plain Hospital of Hope COVID-19 field hospital between 1st January 2021 and 29th February 2021. Patients admitted to the hospital must have been: over 18years of age, diagnosed with COVID-19 via polymerase chain reaction (PCR) test, transferred from a referring facility.

You may not qualify if:

  • No patients were excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mitchells Plain Hospital of Hope Covid-19 Field Hospital, Lentegeur Hospital

Cape Town, Western Province, 7785, South Africa

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Target Duration
2 Months
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

November 3, 2021

First Posted

November 9, 2021

Study Start

February 11, 2021

Primary Completion

March 31, 2021

Study Completion

March 31, 2021

Last Updated

November 9, 2021

Record last verified: 2021-11

Data Sharing

IPD Sharing
Will not share

Individual participant data and hospital level data will be available to the public on completion of the research

Locations