Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 35/100

Failure Rate

5.3%

14 terminated/withdrawn out of 266 trials

Success Rate

92.0%

+5.4% vs industry average

Late-Stage Pipeline

15%

40 trials in Phase 3/4

Results Transparency

22%

35 of 160 completed trials have results

Key Signals

32 recruiting35 with results8 terminated6 withdrawn

Enrollment Performance

Analytics

N/A
131(62.1%)
Phase 2
25(11.8%)
Phase 3
25(11.8%)
Phase 4
15(7.1%)
Phase 1
15(7.1%)
211Total
N/A(131)
Phase 2(25)
Phase 3(25)
Phase 4(15)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (266)

Showing 20 of 266 trials
NCT06281834Phase 1Recruiting

Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention

Role: collaborator

NCT05069688Phase 1Recruiting

Dolutegravir Pharmacokinetics Among HIV/TB Coinfected Children Receiving Standard and High-dose Rifampicin

Role: collaborator

NCT03730181Phase 1Completed

Tuberculosis Clinical Trials Consortium Study 35

Role: collaborator

NCT05653063Active Not Recruiting

ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer

Role: collaborator

NCT06423612Not ApplicableRecruiting

Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA)

Role: collaborator

NCT04446611Not ApplicableCompleted

Clinical Study of STI Screening to Prevent Adverse Birth and New-born Outcomes (Philani Ndiphile)

Role: collaborator

NCT05624931Not ApplicableRecruiting

Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

Role: collaborator

NCT07699393Phase 2Recruiting

Pilot Study of Prenatal Choline Supplementation

Role: collaborator

NCT04395196Phase 2Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Role: collaborator

NCT06962592Not ApplicableRecruiting

Mentor Moms+ Study

Role: collaborator

NCT07518914Not ApplicableRecruiting

Protecting Against Lenacapavir Misinformation With Young Women in Gauteng, South Africa ( PROTECT-L)

Role: collaborator

NCT07032363Not ApplicableRecruiting

Implementing Depression and Adherence Treatment

Role: collaborator

NCT06152003Not ApplicableNot Yet Recruiting

Intervention Development for Syndemics Among PWH in SA

Role: collaborator

NCT07564193Not ApplicableNot Yet Recruiting

The Coach Mpilo Study: Evaluation of a Peer-led Intervention to Promote Engagement in HIV Care for Men Living With HIV

Role: lead

NCT04303104Not ApplicableCompleted

Xpert Active Case-finding Trial 3 (XACT-3)

Role: lead

NCT05220163Not ApplicableActive Not Recruiting

Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19

Role: lead

NCT05933226Not ApplicableActive Not Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Role: collaborator

NCT05007795Not ApplicableNot Yet Recruiting

Test to Treat TB: Impact of Sputum Sequencing-guided Individualised Therapy on Outcomes in Drug-resistant Tuberculosis

Role: lead

NCT06590428Not ApplicableRecruiting

Therapeutic Drug Monitoring for Linezolid in the Treatment of Rifampin-resistant Tuberculosis

Role: collaborator

NCT05333679Not ApplicableCompleted

Urine Tenofovir Point-of-care Test to Identify Patients in Need of ART Adherence Support (UTRA Study)

Role: collaborator