NCT05264948

Brief Summary

Corona Virus - 19 Disease (COVID-19), caused by Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2), first appeared in Wuhan city of Hubei province of China and spread rapidly, causing a pandemic. In the period from the first emergence of the disease to the present, 336,790,193 people have been infected and 5,560,718 people have died. Considering the severity of the disease, some quarantine measures should be applied, as in many infectious diseases, among the first measures taken worldwide to prevent the spread of the virus.It has been suggested in a limited number of studies conducted in the last two years that climatic conditions may be among the main factors affecting the spread of SARS-CoV-2. However, there is no consensus on the effects of factors such as temperature, humidity, and wind on the spread of the disease, and there are conflicting results. The aim of this study is to determine the relationship between the rate of spread of COVID-19, the rate of intensive care hospitalization and fatality, and weather conditions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24,225

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 31, 2021

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

March 1, 2022

Completed
1 day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 2, 2022

Completed
1 day until next milestone

First Posted

Study publicly available on registry

March 3, 2022

Completed
Last Updated

March 3, 2022

Status Verified

March 1, 2022

Enrollment Period

11 months

First QC Date

March 1, 2022

Last Update Submit

March 1, 2022

Conditions

Keywords

COVID-19SARS-CoV-2Seasonal Variation

Outcome Measures

Primary Outcomes (1)

  • The rate of spread of SARS-CoV-2

    Number of Covid-19 cases per day

    284 day

Secondary Outcomes (2)

  • Intensive care hospitalization rate

    284 day

  • Covid-19 fatality rate

    284 day

Interventions

Covid-19 genetic material detection from mouth and nose swab

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with positive PCR test according to laboratory, imaging and PCR test results from adult patients who applied with Covid-19 symptoms or contact history, and patients diagnosed with COVID-19 as a result of imaging and clinical findings were included in the study. Patients under the age of 18 were excluded from these patients.

You may qualify if:

  • Patients with positive PCR test according to laboratory, imaging and PCR test results from adult patients who applied with Covid-19 symptoms or contact history, and patients diagnosed with COVID-19 as a result of imaging and clinical findings were included in the study.

You may not qualify if:

  • Patients under the age of 18 were excluded from these patients.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

IKCU, Atatürk Eğitim ve Araştırma Hastanesi, Acil Tıp

Izmir, 35360, Turkey (Türkiye)

Location

Related Publications (6)

  • Scafetta N. Distribution of the SARS-CoV-2 Pandemic and Its Monthly Forecast Based on Seasonal Climate Patterns. Int J Environ Res Public Health. 2020 May 17;17(10):3493. doi: 10.3390/ijerph17103493.

  • Shaman J, Kohn M. Absolute humidity modulates influenza survival, transmission, and seasonality. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3243-8. doi: 10.1073/pnas.0806852106. Epub 2009 Feb 9.

  • Lipsitch M, Viboud C. Influenza seasonality: lifting the fog. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3645-6. doi: 10.1073/pnas.0900933106. No abstract available.

  • Wu T, Kang S, Peng W, Zuo C, Zhu Y, Pan L, Fu K, You Y, Yang X, Luo X, Jiang L, Deng M. Original Hosts, Clinical Features, Transmission Routes, and Vaccine Development for Coronavirus Disease (COVID-19). Front Med (Lausanne). 2021 Jul 6;8:702066. doi: 10.3389/fmed.2021.702066. eCollection 2021.

  • Tosepu R, Gunawan J, Effendy DS, Ahmad OAI, Lestari H, Bahar H, Asfian P. Correlation between weather and Covid-19 pandemic in Jakarta, Indonesia. Sci Total Environ. 2020 Jul 10;725:138436. doi: 10.1016/j.scitotenv.2020.138436. Epub 2020 Apr 4.

  • Ma Y, Zhao Y, Liu J, He X, Wang B, Fu S, Yan J, Niu J, Zhou J, Luo B. Effects of temperature variation and humidity on the death of COVID-19 in Wuhan, China. Sci Total Environ. 2020 Jul 1;724:138226. doi: 10.1016/j.scitotenv.2020.138226. Epub 2020 Mar 26.

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant professor

Study Record Dates

First Submitted

March 1, 2022

First Posted

March 3, 2022

Study Start

January 31, 2021

Primary Completion

January 1, 2022

Study Completion

March 2, 2022

Last Updated

March 3, 2022

Record last verified: 2022-03

Data Sharing

IPD Sharing
Will share

All data other than the personal information of the participants can be shared.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Starting in January 2023
Access Criteria
IPDs will be shared openly to all scientists without patient names and personal information, and the corrospendence author will be responsible for sharing. All requests by researchers and scientists will be met.

Locations