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South Africa

4107 clinical trials

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Clinical Trials (4107)

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NCT06966700Phase 35 sites

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting

An Observational Study of Participants With Type 3 Von Willebrand Disease on Prophylactic Standard-of-Care Treatment

Active Not Recruiting
NCT05217667Phase 21 site

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

Terminated
NCT06136559Phase 35 sites

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

Recruiting
NCT07181109Phase 331 sites

Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

Recruiting
NCT03486873Phase 37 sites

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Recruiting
NCT04083781Phase 33 sites

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia With Inhibitors

Active Not Recruiting
NCT04082429Phase 32 sites

Research Study to Look at How Well the Drug Concizumab Works in Your Body if You Have Haemophilia Without Inhibitors

Active Not Recruiting
NCT05330325Phase 34 sites

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow

Active Not Recruiting
NCT06158841Phase 33 sites

Study Assessing Activity of Intravenous (IV) Etentamig Monotherapy Versus Standard Available Therapies in Adult Participants With Relapsed or Refractory Multiple Myeloma

Recruiting
NCT05685238Phase 32 sites

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4)

Active Not Recruiting

Chronic Hepatitis B Virus Infection in Zambia

Completed
NCT06739915Not Applicable1 site

Targeted Universal TB Testing With Simultaneous TPT Prescribing Among People Living With HIV in South Africa

Completed
NCT06430801Phase 36 sites

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

Recruiting
NCT07645378Not Applicable1 site

Feasibility Study Comparing One vs Two Probes for Thermal Ablation Among Cervical Cancer Screen Positive WLWH in C1001P-CS9 South Africa

Not Yet Recruiting

PRISMA Maternal and Newborn Health Study

Recruiting
NCT05030428Phase 318 sites

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease

Active Not Recruiting
NCT04607421Phase 33 sites

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT02993523Phase 32 sites

A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy

Active Not Recruiting
NCT05161195Phase 43 sites

Roll-over Study to Allow Continued Access to Ribociclib

Active Not Recruiting