NCT05067036

Brief Summary

This study aims to assess the effect of physical activity on food intake and appetite in older adults (≥ 65 years) and to investigate the relationship between older adults' eating behaviours, body composition and physical activity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
108

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 9, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 7, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 9, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 2, 2021

Completed
1 month until next milestone

First Posted

Study publicly available on registry

October 4, 2021

Completed
Last Updated

October 4, 2021

Status Verified

October 1, 2021

Enrollment Period

4 months

First QC Date

September 2, 2021

Last Update Submit

October 1, 2021

Conditions

Older AdultsPhysical ActivityFood IntakeEating BehaviorBody Composition

Keywords

older adultsappetitephysical activityfood intakebody composition

Outcome Measures

Primary Outcomes (3)

  • Physical Activity Status

    Physical Activity Status is assessed by using Accelerometers ((AX3) (3-Axis Logging Accelerometer)). Participants will wear the accelerometers 24-hour for 7 days. Their moderate and vigorous activity hours will be aggregated and based on this data, they will be divided into three groups as vigorous-moderate-low physical activity.

    7 days

  • Ratings of Appetite

    Appetite is assessed using a 100mm Visual Analogue Scales (VAS, scale 0-100).

    1 day

  • Food Intake

    Food intake is assessed using a 24-hour weighted food diary.

    3 days (2 weekdays and 1 weekend day) while the participants are wearing the accelerometer.

Secondary Outcomes (16)

  • Height

    Day 1

  • Weight

    Day 1

  • BMI

    Day 1

  • % fat mass

    Day 1

  • % lean body mass

    Day 1

  • +11 more secondary outcomes

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

Participants aged older than 65 years.

You may qualify if:

  • Healthy, living independently and self-reported;
  • Aged ≥ 65 years;
  • Having the ability to understand the study procedures.

You may not qualify if:

  • Being obese (BMI \> 30 kg/m2);
  • Smoking more than 10 cigarettes a day;
  • Having a disease such as cardiovascular disease and other chronic diseases (diabetes, thyroid disorders, cancer, heart, lung and kidney disease;
  • Taking medications known to influence appetite, food intake or body weight in the past three months;
  • Changing their diet and exercise in the last 3 months;
  • Having unexpected weight loss in the last 3 months.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Reading

Reading, United Kingdom

Location

Related Publications (5)

  • Morley JE, Silver AJ. Anorexia in the elderly. Neurobiol Aging. 1988 Jan-Feb;9(1):9-16. doi: 10.1016/s0197-4580(88)80004-6.

    PMID: 2898107BACKGROUND

  • Clegg ME, Godfrey A. The relationship between physical activity, appetite and energy intake in older adults: A systematic review. Appetite. 2018 Sep 1;128:145-151. doi: 10.1016/j.appet.2018.05.139. Epub 2018 Jun 7.

    PMID: 29885385BACKGROUND

  • Clarkston WK, Pantano MM, Morley JE, Horowitz M, Littlefield JM, Burton FR. Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults. Am J Physiol. 1997 Jan;272(1 Pt 2):R243-8. doi: 10.1152/ajpregu.1997.272.1.R243.

    PMID: 9039015BACKGROUND

  • Margetts BM, Thompson RL, Elia M, Jackson AA. Prevalence of risk of undernutrition is associated with poor health status in older people in the UK. Eur J Clin Nutr. 2003 Jan;57(1):69-74. doi: 10.1038/sj.ejcn.1601499.

    PMID: 12548299BACKGROUND

  • Dericioglu D, Methven L, Clegg ME. Does physical activity level and total energy expenditure relate to food intake, appetite, and body composition in healthy older adults? A cross-sectional study. Eur J Nutr. 2025 Jan 24;64(2):71. doi: 10.1007/s00394-024-03571-z.

    PMID: 39853478DERIVED

Related Links

MeSH Terms

Conditions

Motor ActivityFeeding Behavior

Condition Hierarchy (Ancestors)

BehaviorBehavior, Animal

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

September 2, 2021

First Posted

October 4, 2021

Study Start

December 9, 2020

Primary Completion

April 7, 2021

Study Completion

May 9, 2021

Last Updated

October 4, 2021

Record last verified: 2021-10

Data Sharing

IPD Sharing
Will not share

No personal identification data will be shared. The study is not under an obligation to share data, however, it is possible that some of the individual (unliked / non-identifiable) data will be useful in a meta-analysis and, hence sharing individual participant data (IPD) will be considered.

Locations

GB(1)