Parental Attitudes and Beliefs Regarding Risks Associated With Opioid Use in Children With Cancer

NCT05055011 | Active Not Recruiting

• 2 other identifiers: 2019-1169NCI-2021-01159
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates parents' attitudes and beliefs on the risks of opioid use in children with cancer. Pain is the common symptom reported by pediatric cancer patients. Opioids are the mainstay in the treatment of cancer-related pain. Despite an almost universal desire to prevent or mitigate pain in their children, parents exhibit complex behaviors from withholding prescribed opioids entirely to giving less than the prescribed analgesic dose of opioid to discontinuing despite ongoing pain. Information gathered from this study may help address a crucial knowledge gap in researchers' understanding of parental attitudes and beliefs regarding the risks associated with opioid use in children and adolescents.

Conditions

Hematopoietic and Lymphoid Cell Neoplasm; Malignant Solid Neoplasm

Outcome Measures

Primary Outcomes (1)

• Parents' level of concern regarding the use of opioids for pain in their children.

  Will be summarized using proportion along with a 95% confidence interval in opioid subgroup and non-opioid subgroup separately.

  through study completion, an average of 1 year

Study Arms (1)

Observational (survey, medical record review)

Parents complete survey over 20 minutes. Patients' medical records are reviewed.

Other: Electronic Health Record Review; Other: Survey Administration

Interventions

Electronic Health Record Review OTHER

Review of medical records

Observational (survey, medical record review)

Survey Administration OTHER

Complete survey

Observational (survey, medical record review)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Parents whose children are on or have been on an opioid for cancer-related pain and parents whose children have not been on an opioid for cancer-related pain

You may qualify if:

• Parents must be at least 18 years old
• The parent must be able to understand, read, write, and speak English
• The parent must provide verbal informed consent
• The child of the parents must be 18 years old or younger
• The child must have a diagnosis of cancer

You may not qualify if:

• A non-cancer diagnosis (neurofibromatosis, Li-Fraumeni syndrome for example).

Sponsors & Collaborators

• M.D. Anderson Cancer Center: lead

Study Sites (1)

M D Anderson Cancer Center

Houston, Texas, 77030, United States

Location

Related Links

• M D Anderson Cancer Center website

MeSH Terms

Conditions

Hematologic Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases

Study Officials

• Kevin Madden, MD

  M.D. Anderson Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 1, 2021
• First Posted: September 23, 2021
• Study Start: December 3, 2020
• Primary Completion (Estimated): December 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: May 4, 2026

Record last verified: 2026-04

Locations

US (1)