Key Insights

Highlights

Success Rate

77% trial completion

Published Results

54 trials with published results (28%)

Research Maturity

63 completed trials (32% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

9.8%

19 terminated out of 194 trials

Success Rate

76.8%

-9.7% vs benchmark

Late-Stage Pipeline

8%

16 trials in Phase 3/4

Results Transparency

86%

54 of 63 completed with results

Key Signals

54 with results77% success19 terminated

Data Visualizations

Phase Distribution

145Total
Not Applicable (39)
Early P 1 (5)
P 1 (34)
P 2 (51)
P 3 (13)
P 4 (3)

Trial Status

Completed63
Active Not Recruiting63
Recruiting30
Terminated19
Withdrawn17
Not Yet Recruiting1

Trial Success Rate

76.8%

Benchmark: 86.5%

Based on 63 completed trials

Clinical Trials (194)

Showing 20 of 20 trials
NCT03816345Phase 1Recruiting

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

NCT02465060Phase 2Active Not Recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

NCT04939090Phase 3Active Not Recruiting

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

NCT04439227Phase 2Active Not Recruiting

Testing AZD1775 as a Potential Targeted Treatment in Cancers With BRCA Genetic Changes (MATCH-Subprotocol Z1I)

NCT04744116Early Phase 1RecruitingPrimary

Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease

NCT02962661Phase 1Recruiting

Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines

NCT05250037Active Not Recruiting

The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The RV-BOS Study)

NCT03712878Phase 2CompletedPrimary

2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies

NCT04439357Phase 2Active Not Recruiting

Testing Trametinib as a Potential Targeted Treatment in Cancers With GNAQ or GNA11 Genetic Changes (MATCH-Subprotocol S2)

NCT04439318Phase 2Active Not Recruiting

Testing Trametinib as a Potential Targeted Treatment in Cancers With NF1 Genetic Changes (MATCH-Subprotocol S1)

NCT04500600Active Not Recruiting

Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic

NCT03023631Phase 4Active Not Recruiting

Gardasil 9 Vaccine in Preventing HPV Infection in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant

NCT04712539Phase 2RecruitingPrimary

Baloxavir and Oseltamivir for the Treatment of Severe Influenza Infection in Immunocompromised Patients

NCT04871477Not Yet Recruiting

Adoption of Audio Recording in the Outpatient Supportive Care Center

NCT02530034Phase 1Active Not Recruiting

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

NCT04177004Phase 1Active Not Recruiting

Human Lysozyme Goat Milk for the Prevention of Graft Versus Host Disease in Patients With Blood Cancer Undergoing a Donor Stem Cell Transplant

NCT03399773Phase 2Active Not Recruiting

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

NCT04439201Phase 2Active Not Recruiting

Testing Palbociclib (PD-0332991) as a Potential Targeted Treatment in Cancers With CCND1, 2, 3 Amplification (MATCH-Subprotocol Z1B)

NCT02710253Phase 2CompletedPrimary

Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

NCT04438382Phase 2TerminatedPrimary

Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis

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