Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 65/100

Failure Rate

20.3%

666 terminated/withdrawn out of 3275 trials

Success Rate

67.0%

-19.5% vs industry average

Late-Stage Pipeline

4%

142 trials in Phase 3/4

Results Transparency

63%

859 of 1355 completed trials have results

Key Signals

549 recruiting859 with results435 terminated231 withdrawn

Enrollment Performance

Analytics

Phase 2
1114(41.3%)
Phase 1
817(30.3%)
N/A
550(20.4%)
Phase 3
108(4.0%)
Early Phase 1
75(2.8%)
Phase 4
34(1.3%)
2698Total
Phase 2(1114)
Phase 1(817)
N/A(550)
Phase 3(108)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (3275)

Showing 20 of 3275 trials
NCT03696784Phase 1Active Not Recruiting

Anti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma

Role: collaborator

NCT05703854Phase 1Suspended

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Role: lead

NCT07377526Phase 1Suspended

TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer

Role: lead

NCT07633756Phase 1Recruiting

A Phase 1b, Open-Label Study Of REC-617, A Selective CDK7 Inhibitor, In Patients With Metastatic Or Unresectable RB1-Negative Leiomyosarcoma After Prior Systemic Therapy

Role: lead

NCT07739745Not ApplicableNot Yet Recruiting

Development Of An Endometrial Cancer Educational Tool

Role: lead

NCT07136077Phase 2Active Not Recruiting

A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy

Role: lead

NCT00633633Not ApplicableActive Not Recruiting

Lifestyle Intervention for Heart Failure

Role: lead

NCT07551583Phase 2Not Yet Recruiting

Phase 2 Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHL

Role: lead

NCT04555577Phase 1Active Not Recruiting

Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma

Role: lead

NCT05039632Phase 1Recruiting

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Role: lead

NCT05663710Phase 1Recruiting

Phase 1b/2 Study of Combination 177Lu Girentuximab Plus Cabozantinib and Nivolumab in Treatment naïve Patients With Advanced Clear Cell RCC

Role: lead

NCT07566364Phase 2Recruiting

Phase 2 Study Of Mosunetuzumab In Patients With Chronic Lymphocytic Leukemia With Positive MRD

Role: lead

NCT05645718Phase 2Recruiting

Study of Pedi-cRIB: Mini-Hyper-CVD With Condensed Rituximab, Inotuzumab Ozogamicin and Blinatumomab (cRIB) for Relapsed Therapy for Pediatric With B-Cell Lineage Acute Lymphocytic Leukemia

Role: lead

NCT07674823Phase 1Not Yet Recruiting

Study Of KITE-753 in R/R B-Cell ALL

Role: lead

NCT04991870Phase 1Recruiting

Phase I CB-NK-TGF-ßR2-/NR3C1- in rGBM

Role: lead

NCT07218315Not ApplicableRecruiting

Nanosecond Pulsed Field Ablation in the Management of T1N0M0 Papillary Thyroid Carcinoma

Role: lead

NCT06967610Phase 2Recruiting

Phase II Study of Combined Pirtobrutinib, Venetoclax and Obinutuzumab (PVO) Time-limited Treatment for Patients With Recurrent Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL).

Role: lead

NCT07137481Phase 2Not Yet Recruiting

Phase II Study of CD5 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Aggressive T Cell Hematological Malignancies

Role: lead

NCT01797523Phase 2Completed

A Phase II, Single-Arm Study of RAD001 (Everolimus), Letrozole, and Metformin in Patients With Advanced or Recurrent Endometrial Carcinoma

Role: lead

NCT07076498Phase 1Recruiting

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Role: lead