NCT04948905

Brief Summary

One of the key features and long considered a fundamental element of Borderline Personality Disorder is the disruption of identity. Autobiographical memory is closely linked to the development and maintenance of a coherent, stable sense of self. It enables the individual to understand who he or she is. The investigators hypothesize that individuals diagnosed with Borderline Personality Disorder have a less coherent, stable sense of the self than healthy controls. The aim of the study is therefore to compare the sense of identity between a group of patients diagnosed with Borderline Personality Disorder and a group of healthy individuals (without Borderline Personality Disorder ). This can be measured by evaluating the content of the self-defining memory using the Self-Defining Memory scale.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Mar 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2021

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

June 17, 2021

Completed
15 days until next milestone

First Posted

Study publicly available on registry

July 2, 2021

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2022

Completed
Last Updated

January 4, 2023

Status Verified

January 1, 2023

Enrollment Period

1.4 years

First QC Date

June 17, 2021

Last Update Submit

January 2, 2023

Conditions

Keywords

Personality Disorder,BorderlinePsychologySelf-Identity

Outcome Measures

Primary Outcomes (2)

  • Sense of Identity in patients diagnosed with Borderline Personality Disorder according to the results of the Self-Defining Memory questionnaire.

    The answers to the Self-Defining Memory questionnaire will be analyzed. At least 3 memories are asked of the participants. Each memory is rated as follows : On a scale of 0 - 6 for each of the following emotions, participants note how they feel when recalling each memory. Happy, Sad, Angry, Fearful, Surprised, Ashamed,Disgusted,Guilty, Interested, Embarrassed, Contemptful, Proud. 0 = not at all, 3 = Moderately and 6 = Extremely. Participants must then use the same scale to indicate the vividness and importance of the memory. They must also note the approximate number of years ago the memory took place (to the nearest whole number).

    Day 7

  • Sense of Identity in healthy controls according to the results of the Self-Defining Memory questionnaire.

    The answers to the Self-Defining Memory questionnaire will be analyzed. At least 3 memories are asked of the participants. Each memory is rated as follows : On a scale of 0 - 6 for each of the following emotions, participants note how they feel when recalling each memory. Happy, Sad, Angry, Fearful, Surprised, Ashamed,Disgusted,Guilty, Interested, Embarrassed, Contemptful, Proud. 0 = not at all, 3 = Moderately and 6 = Extremely. Participants must then use the same scale to indicate the vividness and importance of the memory. They must also note the approximate number of years ago the memory took place (to the nearest whole number).

    Day 7

Secondary Outcomes (8)

  • Self-coherence of self-defining memories in patients diagnosed with Borderline Personality Disorder

    Day 7

  • Self-coherence of self-defining memories in healthy controls

    Day 7

  • Phenomenological details of self-defining memories in patients diagnosed with Borderline Personality Disorder

    Day 7

  • Phenomenological details of self-defining memories in healthy controls

    Day 7

  • Traumas undergone in patients diagnosed with Borderline Personality Disorder: Frequency

    Day 7

  • +3 more secondary outcomes

Other Outcomes (12)

  • Age of patients diagnosed with Borderline Personality Disorder

    Day 0

  • Age of healthy controls

    Day 0

  • Sex of patients diagnosed with Borderline Personality Disorder

    Day 0

  • +9 more other outcomes

Study Arms (2)

Patients diagnosed as having Borderline Personality Disorder

These patients have been diagnosed as having Borderline Personality Disorder according to the Diagnostic and Statistical Manual IV classification after taking the Structured Clinical Interview for DSM-IV Axis I Disorders test.

Other: Evaluation using the Self-Defining Memory Questionnaire

Healthy Controls (Patients not diagnosed as having Borderline Personality Disorder )

These patients have NOT been diagnosed as having Borderline Personality Disorder according to the Diagnostic and Statistical Manual IV classification after taking the Structured Clinical Interview for DSM-IV Axis I Disorders test.

Other: Evaluation using the Self-Defining Memory Questionnaire

Interventions

This questionnaire consists of 3 pages. Page 1 gives a clear, concise definition of a memory that defines the self. This enlightens the subject on what is expected and helps him/her consider the phenomenological characteristics of the Self-Defining Memory. Page 2 recalls the 6 essential characteristics of the Self-Defining Memory. Page 3 allows the practical application of what has been understood about the questionnaire. At least 3 memories are asked of the participants. Each memory is rated as follows : On a scale of 0 - 6 for each of the following emotions, participants note how they feel when recalling each memory. Happy, Sad, Angry, Fearful, Surprised, Ashamed,Disgusted,Guilty, Interested, Embarrassed, Contemptful, Proud. 0 = not at all, 3 = Moderately and 6 = Extremely. Participants must then use the same scale to indicate the vividness and importance of the memory. They must also note the approximate number of years ago the memory took place (to the nearest whole number).

Healthy Controls (Patients not diagnosed as having Borderline Personality Disorder )Patients diagnosed as having Borderline Personality Disorder

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

30 patients diagnosed as having Bordeline Personality Disorder 30 healthy controls recruited from a poster Campaign within the various departments of Nîmes University Hospital, France.

You may qualify if:

  • Subject must have given written consent
  • Subject affiliated or beneficiary of a health insurance plan.
  • Adult subjects between 25 and 55 years of age
  • Oral and written mastery of the French language
  • Subject diagnosed as having borderline personality disorder according to the DSM IV classification

You may not qualify if:

  • Patients without diagnosis of borderline personality disorder according to the DSM IV classification after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test
  • Subjects considered Borderline after taking the SCID II (Structured Clinical Interview for DSM-III-R Axis II Disorders) test
  • Subjects with a score above 8 on the HADS questionnaire corresponding to questionable symptomatology for anxiety and depressive symptoms.
  • Subjects under court protection, guardianship or curatorship
  • Subjects for whom it is impossible to give informed information
  • Subjects participating in a Category 1 or 2 RIPH in the 3 months prior to the study
  • Subject refusing to give written consent
  • Presence of known neurological disease
  • Pregnant or breastfeeding women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nîmes University Hospital

Nîmes, Gard, 30029, France

Location

Related Publications (6)

  • Moffitt KH, Singer JA. Continuity in the Life Story: Self-Defining Memories, Affect, and Approach/Avoidance Personal Strivings. Journal of Personality.1994; 62(1), 21-43

    BACKGROUND
  • Singer, J. A., & Moffitt, K. H. An experimental investigation of specificity and generality in memory narratives. Imagination, Cognition and Personality. PsycINFO Database Record (1991-1992)11(3), 233-257.

    BACKGROUND
  • Bluck S, Alea N. Crafting the TALE: construction of a measure to assess the functions of autobiographical remembering. Memory. 2011 Jul;19(5):470-86. doi: 10.1080/09658211.2011.590500.

    PMID: 21864212BACKGROUND
  • Johnson MK, Foley MA, Suengas AG, Raye CL. Phenomenal characteristics of memories for perceived and imagined autobiographical events. J Exp Psychol Gen. 1988 Dec;117(4):371-6.

    PMID: 2974863BACKGROUND
  • Bernstein, D. P., Fink, L., Handelsman, L., & Foote, J. Childhood Trauma Questionnaire (CTQ) [Database record].(1994) APA PsycTests. https://doi.org/10.1037/t02080-000

    BACKGROUND
  • Spitzer, Robert L, Williams Janet BW, Gibbon Miriam, First Michael B, Structured Clinical Interview for DSM-III-R Axis II Disorders,(SCID-II), Washington, D.C.: American Psychiatric Press, Inc., 1990

    BACKGROUND

MeSH Terms

Conditions

Borderline Personality DisorderPersonality Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Jorge LOPEZ-CASTROMAN, Prof.

    Psychiatric Unit, Nîmes University Hospital, France

    PRINCIPAL INVESTIGATOR
  • Stéphane RAFFARD, Prof.

    Montpellier University III, Laboratoire Epsylon, Route de Mende, 34090 Montpellier, France

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 17, 2021

First Posted

July 2, 2021

Study Start

March 1, 2021

Primary Completion

July 31, 2022

Study Completion

July 31, 2022

Last Updated

January 4, 2023

Record last verified: 2023-01

Locations