Novel Equation for Estimating Resting Energy Expenditure in Dialysis Patients

NCT04947839 | Completed

• 1 other identifier: REE equation in dialysis
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 2

Brief Summary

The energy and nutrition states are closely associated with dialysis patients' complications and outcomes. To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations do not focus on and applicable to peritoneal dialysis patients, so we aim to develop and validate an equation for estimating resting energy expenditure in peritoneal patients.

Conditions

Resting Energy Expenditure; Peritoneal Dialysis; Equation

Outcome Measures

Primary Outcomes (2)

• Novel equation development

  Developed equation for estimating resting energy expenditure in peritoneal dialysis patients

  March 18, 2021 to October 30, 2021

• Novel equation validation

  Validate the novel equation with resting energy expenditure obtained by indirect calorimetry (IC).

  October 30, 2021 to December 30, 2021

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All peritoneal dialysis patients meet the inclusion and exclusion criteria in a single center

You may qualify if:

• Peritoneal dialysis patients and hemodialysis patients
• Dialysis length \>3 months
• \>18 years old
• Consented to participate in all aspects of the study

You may not qualify if:

• Acute complications to hospitalization 1 month prior to the study;
• Acute or chronic infections, cancer, and other wasting diseases in the past year;
• Thyroid dysfunction;
• Acute onset of podagra; Musculoskeletal diseases;
• Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);
• History of hormonal drug use;
• During pregnancy or lactation;
• Can not maintain posture and complete the REE test.

Sponsors & Collaborators

• Peking University First Hospital: lead

Study Sites (2)

Peking University First Hospital

Beijing, Beijing Municipality, 100034, China

Location

Peking Haidian Hospital

Beijing, China

Location

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor in Renal Division，Department of Medicine

Study Record Dates

• First Submitted: June 24, 2021
• First Posted: July 1, 2021
• Study Start: March 18, 2021
• Primary Completion: June 28, 2022
• Study Completion: July 8, 2022
• Last Updated: September 29, 2022

Record last verified: 2022-09

Locations

CN (2)