NCT03571451

Brief Summary

Increasing the proportion of patients on peritoneal dialysis (PD) may relieve the financial burden caused by the growing number of patients with end-stage renal disease (ESRD). The investigators are developing a PD database in China using peritoneal dialysis telemedicine-assisted platform (PD TAP). The survival rate and technique survival rate of PD patients, as well as risk factors associated with survival and technique survival will be analyzed through PD TAP.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
7,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2016

Longer than P75 for all trials

Geographic Reach
1 country

27 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2016

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

June 20, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 27, 2018

Completed
7.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2025

Completed
Last Updated

October 25, 2023

Status Verified

October 1, 2023

Enrollment Period

9.5 years

First QC Date

June 20, 2018

Last Update Submit

October 23, 2023

Conditions

Keywords

peritoneal dialysissurvival ratetechnique survival raterisk factorsend stage renal disease

Outcome Measures

Primary Outcomes (2)

  • All-cause death

    All-cause death refers to the number of patients who died within the anticipated time frame. For example death caused by CVD, systemic infection, malignancies (according to the WHO classification), and protein-energy wasting.

    10 years

  • Transfer to hemodialysis

    Transfer to hemodialysis refers to the number of patients who were Transfer to hemodialysis from PD due to any cause within the anticipated time frame. For example, caused by dialysis inadequacy, volume overload, infection-related (peritonitis and exitsite infection), catheter dysfunction (catheter blockage and displacement), ultrafiltration failure, et al.

    10 years

Secondary Outcomes (6)

  • Peritonitis

    10 years

  • Exit-site/tunnel infection

    10 years

  • Cardiovascular events

    10 years

  • Abdominal wall complications

    10 years

  • others

    10 years

  • +1 more secondary outcomes

Eligibility Criteria

Age14 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with end-stage renal disease receiving maintenance peritoneal dialysis

You may qualify if:

  • End-stage renal disease patients receiving maintenance peritoneal dialysis;
  • more than 14 years old

You may not qualify if:

  • receiving temporary PD due to acute kidney injury
  • loss to follow up without any outcomes recorded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (27)

The second affiliated hospital of Anhui Medical University

Hefei, Anhui, China

RECRUITING

Peking University First Hospital

Beijing, Beijing Municipality, 100034, China

RECRUITING

People's Hospital of Gansu Province

Lanzhou, Gansu, China

RECRUITING

Peking University Shenzhen Hospital

Shenzhen, Guangdong, China

RECRUITING

Cangzhou central hospital

Cangzhou, Hebei, China

RECRUITING

People's hospital of Cangzhou

Cangzhou, Hebei, China

RECRUITING

Handan Central Hospital

Handan, Hebei, China

RECRUITING

People's hospital of Langfang

Langfang, Hebei, China

RECRUITING

The second hospital of Hebei medical university

Shijiazhuang, Hebei, China

RECRUITING

The third hospital of Hebei Medical University

Shijiazhuang, Hebei, China

RECRUITING

The second affiliated hospital of Harbin Medical University

Harbin, Heilongjiang, China

RECRUITING

Pingdingshan People's Hospital No.1

Pingdingshan, Henan, China

RECRUITING

First affiliated hospital of Zhengzhou University

Zhengzhou, Henan, China

RECRUITING

The first affiliated hospital of Baotou Medical College

Baotou, Inner Mongolia, China

RECRUITING

The first hospital of Jilin University

Changchun, Jilin, China

RECRUITING

Shengjing hospital affiliated to China Medical University

Liaoyang, Liaoning, China

RECRUITING

People's Hospitel of Qinghai Province

Xining, Qinghai, China

RECRUITING

The first people's hospital of Xining

Xining, Qinghai, China

RECRUITING

Taiyuan central hospital

Taiyuan, Shanxi, China

RECRUITING

The second hospital of Shanxi Medical University

Taiyuan, Shanxi, China

RECRUITING

The People's Hospital of Chuxiong Yi Autonomous Prefecture

Chuxiong, Yunnan, China

RECRUITING

Beijing Charity Hospital

Beijing, China

RECRUITING

Beijing dongzhimen Hospital

Beijing, China

RECRUITING

Beijing haidian hospital

Beijing, China

RECRUITING

Beijing miyun district hospital

Beijing, China

RECRUITING

Peking University People's Hospital

Beijing, China

RECRUITING

Xinqiao hospital of the Third Military Medical University

Chongqing, China

RECRUITING

Related Publications (1)

  • Li X, Ma T, Hao J, Song D, Wang H, Liu T, Xu X, Dong J. The relationship between exercise and the occurrence of abdominal wall complications in patients on peritoneal dialysis. BMC Nephrol. 2025 Jul 15;26(1):389. doi: 10.1186/s12882-025-04317-7.

Biospecimen

Retention: SAMPLES WITH DNA

All participants were voluntary to collect the blood, urine, DNA and tissue specimen and signed the informed consent form.

MeSH Terms

Conditions

Kidney Failure, Chronic

Condition Hierarchy (Ancestors)

Renal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Jie Dong, MD,Ph.D.

CONTACT

Tian-tian Ma, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Peritoneal dialysis center

Study Record Dates

First Submitted

June 20, 2018

First Posted

June 27, 2018

Study Start

June 1, 2016

Primary Completion

December 1, 2025

Study Completion

December 1, 2025

Last Updated

October 25, 2023

Record last verified: 2023-10

Locations