Novel Equation for Estimating Resting Energy Expenditure
1 other identifier
observational
300
1 country
1
Brief Summary
The energy and nutrition states are closely associated with CKD patients complications and outcomes.To reach the energy balance target, we need the accurate resting energy expenditure level of patients. Traditional equations are not applicable to CKD patients,so we aim to develop and validate a equation for estimating resting energy expenditure in CKD patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2017
Typical duration for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
December 14, 2017
CompletedStudy Start
First participant enrolled
December 14, 2017
CompletedFirst Posted
Study publicly available on registry
December 19, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 31, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2020
CompletedOctober 14, 2020
October 1, 2020
2.1 years
December 14, 2017
October 13, 2020
Conditions
Outcome Measures
Primary Outcomes (2)
Novel equation development
Developed equation for estimating REE in CKD 3-5 stages patients
September 1, 2017 to June 1, 2018
Novel equation validation
Validate the noval equation with REE obtained by indirect calorimetry (IC).
June 1, 2018 to March 1, 2019
Eligibility Criteria
chronic kidney disease 3-5 stages
You may qualify if:
- CKD 3-5 stages
- Age:18-80 years old
You may not qualify if:
- Dialysis and kidney transplantation;
- Acute complications to hospitalization
- month prior to the study;
- Acute or chronic infections, cancer and other wasting diseases in the past year;
- Thyroid dysfunction;
- Acute onset of podagra; Musculoskeletal diseases;
- Respiratory diseases (asthma, pleural effusion, pneumothorax, COPD);
- History of hormonal drugs use;
- During pregnancy or lactation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Renal Division and Institute of Nephrology, Peking University First Hospital
Beijing, Beijing Municipality, 100034, China
Related Publications (1)
Xu X, Yang Z, Ma T, Li Z, Chen Y, Zheng Y, Dong J. Novel equation for estimating resting energy expenditure in patients with chronic kidney disease. Am J Clin Nutr. 2021 Jun 1;113(6):1647-1656. doi: 10.1093/ajcn/nqaa431.
PMID: 33693520DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Jie Dong
Renal Division and Institute of Nephrology, Peking University First Hospital
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- CROSS SECTIONAL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Clinical Professor in Renal Division, Department of Medicine
Study Record Dates
First Submitted
December 14, 2017
First Posted
December 19, 2017
Study Start
December 14, 2017
Primary Completion
January 31, 2020
Study Completion
February 1, 2020
Last Updated
October 14, 2020
Record last verified: 2020-10