NCT04891627|Completed
Gingival Crevicular IL-34 and CSF-1 Levels in Patients With Periodontitis and Uncontrolled Type 2 Diabetes
Usak University Faculty of Dentistry
Loading search results
Usak University Faculty of Dentistry
Sponsor study identifier
observational
76
1 country
1
Study Start
January 6, 2021
Actual (reported)Primary Completion
April 21, 2021
Actual (reported)Study Completion
May 4, 2021
Actual (reported)Type 2 diabetes mellitus is a metabolic disorder. There is a bidirectional association between periodontal disease and DM. Currently there is no data relationship between CSF-1 and IL-34, periodontal disease and diabetes.The aim of this study to investigate GCF levels of IL-34 and CSF-1 in periodontitis subjects with diabetes.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 4, 2021
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 6, 2021
Actual (reported)April 21, 2021
Actual (reported)May 4, 2021
Actual (reported)May 13, 2021
Actual (reported)May 18, 2021
Actual (reported)It was aimed to compare IL-34 levels by taking gingival crevicular fluid in systemic healthy, periodontitis and diabetic patients with periodontitis groups.
GCF was taken interproximal region.
GCF samples taken within the 1. week after the clinical examination of the patient
It was aimed to compare CSF-1 levels by taking gingival crevicular fluid in systemic healthy, periodontitis and diabetic patients with periodontitis groups.
GCF samples taken within the 1. week after the clinical examination of the patient
individuals with clinically healthy gingiva BOP score less than 10% and PD≤3mm
interdental AL ≥5 mm
HbA1c ≥6.5%
GCF samples were collected in the morning hours 24-48 hours after clinical periodontal measurement.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
individuals have diabetes and periodontitis
University of Usak
Uşak, 64200, Turkey (Türkiye)
Dikilitas A, Karaaslan F, Evirgen S, Ertugrul AS. Gingival crevicular fluid CSF-1 and IL-34 levels in patients with stage III grade C periodontitis and uncontrolled type 2 diabetes mellitus. J Periodontal Implant Sci. 2022 Dec;52(6):455-465. doi: 10.5051/jpis.2106260313. Epub 2022 Apr 12.
Gingival crevicular fluid
ahu dikilitas
University of Usak
76 participants (actual enrollment reported by the registry).
First Submitted
May 13, 2021
First Posted
May 18, 2021
Study Start
January 6, 2021
Actual (reported)Local Delivery of Lactobacillus Reuteri Probiotic as An Adjunct to Non-surgical Periodontal Therapy in Patients With Stage II, III, and IV Periodontitis and Type 2 Diabetes Mellitus
Contact the study team to confirm eligibility.
Primary Completion
April 21, 2021
Actual (reported)Study Completion
May 4, 2021
Actual (reported)Last Updated
January 12, 2023
Record last verified: 2023-01
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: