Effect of Carbohydrate-protein Co-ingestion on Short-term Recovery

NCT04859491 | Completed

• 1 other identifier: MCAs and Short-Term Recovery
• Study Type: interventional
• Target: 24
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine whether the consumption of a carbohydrate, carbohydrate plus protein, or placebo sports drink during a 2-hour recovery period effectively moderates performance decrements during a subsequent bout of high-intensity exercise. This information will benefit any endurance-trained masters class athlete who may need to compete or train multiple times a day.

Conditions

Dietary Supplementations

Keywords

glycogen; glucose; aerobic exercise; time to exhaustion; supplementation; protein; endurance; recovery

Outcome Measures

Primary Outcomes (1)

• Time to Exhaustion (TTE)

  Participants cycle for as long as possible at 90% of peak power output (watts)

  Visit #3 (Day 7)

Secondary Outcomes (2)

• Heart Rate Variability (HRV)

  Visit #3 (Day 7)

• Sweat Rate (SR)

  Visit #3 (Day 7)

Study Arms (3)

Carbohydrate

ACTIVE COMPARATOR

Carbohydrate in the amount of 1.2 g/kg of body weight (bw). Gatorade®, Chicago, IL, USA.

Dietary Supplement: Carbohydrate

Carbohydrate-Protein

ACTIVE COMPARATOR

Carbohydrate in the amount of 0.8 g/kg bw (Gatorade®, Chicago, IL, USA) plus protein in the amount of 0.4 g/kg bw (biPro Elite, Agropur Inc., Appleton, WI, USA).

Dietary Supplement: Carbohydrate-Protein

Placebo

PLACEBO COMPARATOR

Flavored water (G Zero, Gatorade®, Chicago, IL, USA).

Dietary Supplement: Placebo

Interventions

Carbohydrate DIETARY_SUPPLEMENT

Participants have a one in three chance of consuming a carbohydrate beverage between two bouts of high-intensity exercise.

Also known as: CHO

Carbohydrate

Carbohydrate-Protein DIETARY_SUPPLEMENT

Participants have a one in three chance of consuming a carbohydrate-protein beverage between two bouts of high-intensity exercise.

Also known as: CHO-P

Carbohydrate-Protein

Placebo DIETARY_SUPPLEMENT

Participants have a one in three chance of consuming a placebo beverage between two bouts of high-intensity exercise.

Also known as: PLA

Placebo

Eligibility Criteria

• Age: 35 Years - 59 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Men between the ages of 35 and 59 years
• Free of any physical limitations as determined by the Exercise Preparticipation Health Screening Questionnaire for Exercise Professionals (PHSQEP), and a Physical Activity Readiness Questionnaire for Everyone (PAR-Q+)
• Regularly engaged in endurance exercise (running, cycling, swimming) for a minimum of three years, a weekly training volume of 5-10 hours, and a maximal oxygen uptake of 45.00 ml·kg-1·min-1 or higher as determined by completion of VO2peak assessment (Visit #1).

You may not qualify if:

• Recent musculoskeletal injuries or surgeries
• Any chronic illness that requires continuous medical care
• Current incarceration, cognitive impairment or inability to provide consent
• Present or past use of performance-enhancing drugs

Sponsors & Collaborators

• Erica Goldstein: lead

Study Sites (1)

University of Central Florida

Orlando, Florida, 32816, United States

Location

Related Publications (3)

• McCarthy DG, Spriet LL. Performance Effects of Carbohydrate Ingestion Between Bouts of Intense Aerobic Interval Exercise. Int J Sports Physiol Perform. 2020 Feb 1;15(2):262-267. doi: 10.1123/ijspp.2019-0239. Epub 2019 Jun 12.

  PMID: 31188694 RESULT

• Alghannam AF, Jedrzejewski D, Bilzon J, Thompson D, Tsintzas K, Betts JA. Influence of Post-Exercise Carbohydrate-Protein Ingestion on Muscle Glycogen Metabolism in Recovery and Subsequent Running Exercise. Int J Sport Nutr Exerc Metab. 2016 Dec;26(6):572-580. doi: 10.1123/ijsnem.2016-0021. Epub 2016 Aug 24.

  PMID: 27097042 RESULT

• Berardi JM, Price TB, Noreen EE, Lemon PW. Postexercise muscle glycogen recovery enhanced with a carbohydrate-protein supplement. Med Sci Sports Exerc. 2006 Jun;38(6):1106-13. doi: 10.1249/01.mss.0000222826.49358.f3.

  PMID: 16775553 RESULT

MeSH Terms

Interventions

Carbohydrates

Study Officials

• Jeffrey Stout, PhD

  University of Central Florida

  STUDY CHAIR

• Erica Goldstein, MS

  University of Central Florida

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: The primary investigator will not be blinded to the treatment groups. However, both the research assistants responsible for administering the experimental protocol (aerobic interval and time to exhaustion testing) and the participants will be.
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Graduate Research Associate

Model Details: Participants will be randomized to one of three groups: isocaloric carbohydrate (1.2 g/kg of body weight), carbohydrate-protein (0.8 g/kg body weight carbohydrate + 0.4 g/kg body weight protein), or placebo (flavored water). All three beverages will have a similar appearance and taste and participants will be blinded to the contents. All beverages will contain the same volume of fluid (1 liter).

Study Record Dates

• First Submitted: March 30, 2021
• First Posted: April 26, 2021
• Study Start: July 22, 2021
• Primary Completion: December 5, 2021
• Study Completion: December 5, 2021
• Last Updated: May 17, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)