Contribution of the Somatosensory System to Speech Perceptual Processing

NCT04818021 | Terminated

• 2 other identifiers: 2000025475_bR01DC017439
• Study Type: interventional
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

These studies test the hypothesis that the repeated pairing of somatosensory inputs with speech sounds, such as occurs during speech motor learning, results in changes to the perceptual classification of speech sounds.

Conditions

Speech; Consolidation

Outcome Measures

Primary Outcomes (2)

• Speech Motor Learning

  Learning is assessed as the change in speech sounds (speech formant frequencies) on a 0 to 100 scale.

  Performance as measured at the end of learning (30 minute session)

• Speech Perception

  Auditory speech perception evaluates auditory classification and is assessed on a 0 to 100 scale. All conditions of skin stretch involve the same speech perception task.

  Perception is evaluated prior to and after perceptual training (30 minute session)

Study Arms (4)

Adaptation to Altered Auditory Feedback

EXPERIMENTAL

Adaptation to Altered Auditory Feedback

Behavioral: Adaptation

Adaptation to Altered Auditory Feedback + Forward Skin Stretch

EXPERIMENTAL

Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Behavioral: Adaptation; Behavioral: Facial Skin Stretch

Adaptation to Altered Auditory Feedback + Backward Skin Stretch

EXPERIMENTAL

Adaptation to Altered Auditory Feedback + Backward Skin Stretch

Behavioral: Adaptation; Behavioral: Facial Skin Stretch

Speech Repetition Control

EXPERIMENTAL

Speech Repetition Control

Behavioral: Adaptation

Interventions

Adaptation BEHAVIORAL

Sensorimotor adaptation in speech

Adaptation to Altered Auditory Feedback; Adaptation to Altered Auditory Feedback + Backward Skin Stretch; Adaptation to Altered Auditory Feedback + Forward Skin Stretch; Speech Repetition Control

Facial Skin Stretch BEHAVIORAL

Facial skin stretch

Adaptation to Altered Auditory Feedback + Backward Skin Stretch; Adaptation to Altered Auditory Feedback + Forward Skin Stretch

Eligibility Criteria

• Age: 21 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• right handed adults
• no known physical or neurological abnormalities

You may not qualify if:

• patients with:
• cardiac pacemaker
• surgical clips or values on the heart
• implants
• metal or metallic fragments in any part of the body
• pregnancy
• claustrophobia
• a personal or family history of epilepsy
• currently taking antipsychotic drugs
• currently taking antidepressant drugs
• currently taking antianxiety drugs.

Sponsors & Collaborators

• National Institute on Deafness and Other Communication Disorders (NIDCD): collaborator
• Yale University: lead
• McGill University: collaborator

Study Sites (1)

McGill University

Montreal, Quebec, H3A1G1, Canada

Location

MeSH Terms

Conditions

Speech

Interventions

Acclimatization

Condition Hierarchy (Ancestors)

Verbal Behavior; Communication; Behavior

Intervention Hierarchy (Ancestors)

Adaptation, Physiological; Physiological Phenomena; Adaptation, Biological; Biological Phenomena

Study Officials

• David Ostry

  Haskins Laboratories

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 19, 2021
• First Posted: March 26, 2021
• Study Start: August 1, 2019
• Primary Completion: July 31, 2025
• Study Completion: July 31, 2025
• Last Updated: February 19, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)