NCT04752670

Brief Summary

This is a prospective registry of all patients who endoscopic submucosal dissection (ESD), per-oral endoscopic myotomy (POEM) and gastric per-oral endoscopic myotomy (G-POEM) using ConMed Electrosurgical unit for submucosal Dissection at Baylor St Luke's Medical Center. Collected information includes; procedure technical success rate, duration, periprocedural complications and ease of use.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started May 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 9, 2021

Completed
3 days until next milestone

First Posted

Study publicly available on registry

February 12, 2021

Completed
3 months until next milestone

Study Start

First participant enrolled

May 27, 2021

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 2, 2022

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2022

Completed
Last Updated

May 27, 2022

Status Verified

May 1, 2022

Enrollment Period

9 months

First QC Date

February 9, 2021

Last Update Submit

May 26, 2022

Conditions

Keywords

Endoscopic Submucosal DissectionPer-Oral Endoscopic Myotomy (POEM)Gastric Per-Oral Endoscopic Myotomy (G-POEM)

Outcome Measures

Primary Outcomes (1)

  • Technical Success rate

    Defined as the ability to perform the entire procedure using the ConMed Beamer electrosurgical system

    1 year

Secondary Outcomes (3)

  • Procedure Time

    1 year

  • Adverse Events

    1 year

  • Adverse Events

    1 year

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

All patients referred for an ESD, POEM or GPOEM satisfying all eligibility criteria will be eligible for the study.

You may qualify if:

  • Patient is ≥ 18 years old
  • Patient is capable of providing informed consent
  • Patient is referred for endoscopic submucosal dissection, per-oral endoscopic myotomy, or gastric per-oral endoscopic myotomy

You may not qualify if:

  • Patient is \< 18 years old
  • Patient refused and/or unable to provide consent
  • Patient is a pregnant woman

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Baylor St. Lukes Medical Center (BSLMC)

Houston, Texas, 77030, United States

Location

MeSH Terms

Conditions

Gastrointestinal NeoplasmsEsophageal AchalasiaGastroparesis

Condition Hierarchy (Ancestors)

Digestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesEsophageal Motility DisordersDeglutition DisordersEsophageal DiseasesStomach DiseasesParalysisNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
4 Weeks
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D. Director of Advanced Endoscopy Assistant Professor of Medicine - Gastroenterology Section

Study Record Dates

First Submitted

February 9, 2021

First Posted

February 12, 2021

Study Start

May 27, 2021

Primary Completion

March 2, 2022

Study Completion

May 1, 2022

Last Updated

May 27, 2022

Record last verified: 2022-05

Data Sharing

IPD Sharing
Will not share

This is a prospective single-center registry study.

Locations