Different Intra-abdominal Pressures and Optic Nerve Size

NCT04556877 | Completed

• 1 other identifier: TUTF 2018/230
• Study Type: observational
• Target: 78
• Locations: 1 country
• Sites: 1

Brief Summary

In intensive care patients, high intraabdominal pressure is frequently encountered. Intra-abdominal pressure is often measured as high, especially after major abdominal surgery procedures. In recent years, various studies have reported that the increase in optic nerve diameter measured by ultrasound correlates with the level of intracranial pressure. Optic nerve diameter measurement with ultrasound is a non-invasive procedure. Intra-abdominal pressure measurements are also routinely performed in intensive care patients. In the measurement of abdominal pressure, the bladder catheter, which is already available in every patient who comes to intensive care, is used. In this study, the intra-abdominal pressure values present in the file of each patient undergoing major abdominal surgery who were taken to intensive care unit will be taken. Orbital USG will be performed on the 6th, 12th and 24th hours on admission to the intensive care unit to measure the diameter of the optic nerve, and the relationship between the intra-abdominal pressure value and optic nerve diameters will be investigated.

Conditions

Major Surgery; Intraabdominal Hypertension; Optic Nerve Congestion

Outcome Measures

Primary Outcomes (4)

• optic nerve diameter

  measuring optic nerve diameter

  within 2 hours of admission

• optic nerve diameter

  measuring optic nerve diameter

  at 6.hour

• optic nerve diameter

  measuring optic nerve diameter

  at 12.hour

• optic nerve diameter

  measuring optic nerve diameter

  at 24.hour

Study Arms (3)

Intraabdominal pressure under 12 mmHg

Patients with intraabdominal pressure under 12 mmHg

Procedure: Intraabdominal pressure and optic nerve diameters

Intraabdominal pressure between 12-20 mmHg

Patients with intraabdominal pressure between 12-20 mmHg

Procedure: Intraabdominal pressure and optic nerve diameters

Intraabdominal pressure over 20 mmHg

Patients with intraabdominal pressure over 20 mmHg

Procedure: Intraabdominal pressure and optic nerve diameters

Interventions

Intraabdominal pressure and optic nerve diameters PROCEDURE

Measuring Intraabdominal pressure with a Foley cathater and measuring optic nerve diameters with a USG

Intraabdominal pressure between 12-20 mmHg; Intraabdominal pressure over 20 mmHg; Intraabdominal pressure under 12 mmHg

Eligibility Criteria

• Age: 18 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Postoperative patients followed in intensive care

You may qualify if:

• Having had major abdominal surgery

You may not qualify if:

• pregnant patients
• Patients whose bladder catheter cannot be inserted
• Patients with diagnosed or suspected brain death

Sponsors & Collaborators

• Trakya University: lead

Study Sites (1)

Trakya University

Edirne, 22030, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Intra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Compartment Syndromes; Muscular Diseases; Musculoskeletal Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Prof

Study Record Dates

• First Submitted: September 7, 2020
• First Posted: September 21, 2020
• Study Start: June 15, 2018
• Primary Completion: June 15, 2020
• Study Completion: June 15, 2020
• Last Updated: September 21, 2020

Record last verified: 2020-09

Locations

TU (1)