Intra-abdominal Hypertension and Associated Factors Among Patients Admitted in Intensive Care Units in Uganda.

NCT03567265 | Completed

• 2 other identifiers: MREC 1254IAH in ug
• Study Type: observational
• Target: 126
• Locations: 1 country
• Sites: 1

Brief Summary

The study was carried out to determine the prevalence,incidence and factors associated with intra-abdominal hypertension among patients admitted in three intensive care units in Kampala Uganda. It was a multi-center prospective cohort study carried out in three intensive care units where 126 patients that met the eligibility criteria were included in the study,demographics,of these were recorded and intra-abdominal pressure measured using the intra-vesical technique at 0,24,and 72 hours.data entry was done using epi-data version 3.1.Data analysis is on going.

Conditions

Intra-Abdominal Hypertension

Outcome Measures

Primary Outcomes (1)

• Intra-abdominal Hypertension

  Intra-abdominal pressure was measured using the intra-vesicular technique.Three measurements were done for each patient at time intervals of 0,24 and 72 hours.This was recorded in a questionnaire, the mean and maximum Intra-abdominal pressure were recorded.Intra-abdominal Hypertension was defined according to the Word Society of Abdominal Compartment Syndrome.

  6 months

Secondary Outcomes (3)

• To determine 28_ day ICU mortality of patients with intra-abdominal hypertension.

  6 months

• To determine duration of mechanical ventilation among patients with intra-abdominal hypertension

  6 months

• To determine the length of ICU stay among patients with intra-abdominal hypertension

  6 months

Eligibility Criteria

• Age: 1 Year+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study enrolled critically ill patients admitted in three intensive care units in Kampala Uganda

You may qualify if:

• All patients admitted to the three intensive care units and were catheterized Patients admitted for more than 24 hours were recruited in the study Patients aged one year and above.

You may not qualify if:

• Patients in which urethral catheterization was not required
• The patients that were below one year
• Patients with contraindications to intra-vesical pressure measurement including: pelvic fracture, haematuria, or neurogenic bladder.
• Pregnant women
• Patients admitted for less than 24 hours into the ICU

Sponsors & Collaborators

• Makerere University: lead

Study Sites (1)

Nansubuga Phiona

Kampala, +256, Uganda

Location

MeSH Terms

Conditions

Intra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Compartment Syndromes; Muscular Diseases; Musculoskeletal Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Phiona Nansubuga, MBCHB

  Makerere University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: April 26, 2018
• First Posted: June 25, 2018
• Study Start: September 1, 2017
• Primary Completion: February 28, 2018
• Study Completion: February 28, 2018
• Last Updated: June 25, 2018

Record last verified: 2018-06

Locations

UG (1)