Application of Enteral Nutrition Program in Patients With Intra-abdominal Hypertension Oriented by Intra-abdominal Pressure

NCT05732545 | Completed

• 1 other identifier: 2021-0899
• Study Type: interventional
• Target: 218
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, relevant contents of the enteral nutrition nursing programs for severe patients with abdominal pressure were systematically searched, and quality evaluation was carried out based on existing evidence. Based on evidence-based evidence, an enteral nutrition nursing program for patients with abdominal pressure was constructed, to improve the feed tolerance of patients with abdominal pressure, increase nutritional compliance rate, and improve patient prognosis.

Conditions

Intra-Abdominal Hypertension

Keywords

Intra-Abdominal Hypertention; Enteral Nutrition; Feeding Intolerance

Outcome Measures

Primary Outcomes (1)

• Incidence of feeding intolerance

  Incidence of feeding intolerance: refers to the frequency of new cases of feeding intolerance within 7 days after the initiation of enteral nutrition.

  7 days

Secondary Outcomes (1)

• The standard rate of feeding

  7 days

Study Arms (2)

enteral nutrition program by intra-abdominal pressure

EXPERIMENTAL

enteral nutrition program for patients with intra-abdominal hypertension guided by intra-abdominal pressure

Behavioral: enteral nutrition program for patients with abdominal hypertension guided by abdominal pressure

Routine nursing measures

NO INTERVENTION

Routine nursing measures

Interventions

enteral nutrition program for patients with abdominal hypertension guided by abdominal pressure BEHAVIORAL

There are 4 aspects of intra-abdominal pressure monitoring, source control and treatment for the etiology of increased abdominal pressure, enteral nutrition program, enteral nutrition tolerance evaluation and treatment

enteral nutrition program by intra-abdominal pressure

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• mmHg≤ intraperitoneal pressure ≤20mmHg (1mmHg=0.133kPa)
• ≥18 years of age
• Consistent with the indications of early enteral nutrition
• Patients with nutritional risk, gastrointestinal function, or partial gastrointestinal function and unable to eat through the mouth
• Stable hemodynamics (MAP \> 65mmHg, blood lactic acid \< 4mmol/L, and vasoactive drugs in the process of reduction or withdrawal)
• Patients or their family members sign the informed consent

You may not qualify if:

• Pregnant or lactating female patients
• Patients with recent abdominal surgery
• Patients with a large number of abdominal effusions;
• There are contraindications to enteral nutrition
• Uncontrolled shock
• Uncontrolled hypoxemia and acidosis
• Uncontrolled upper gastrointestinal bleeding
• GRV \> 500mL/ 6h
• Intestinal ischemia
• Intestinal obstruction
• Abdominal space syndrome (ACS)
• High fistula without distal feeding

Sponsors & Collaborators

• Second Affiliated Hospital, School of Medicine, Zhejiang University: lead

Study Sites (1)

Feng Xiuqin

Hangzhou, 310000, China

Location

MeSH Terms

Conditions

Intra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Compartment Syndromes; Muscular Diseases; Musculoskeletal Diseases; Vascular Diseases; Cardiovascular Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: February 8, 2023
• First Posted: February 17, 2023
• Study Start: January 1, 2022
• Primary Completion: October 1, 2022
• Study Completion: November 1, 2022
• Last Updated: February 23, 2023

Record last verified: 2023-02

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)