Intra-abdominal Hypertension in Critically Ill Patients

NCT02514135 | Completed DMC

• 1 other identifier: WesternUCanada
• Study Type: observational
• Target: 286
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.

Conditions

Intra-Abdominal Hypertension; Abdominal Compartment Syndrome

Outcome Measures

Primary Outcomes (1)

• Mortality

  As measured prospectively by patient death in the ICU

  While patient in-hospital, expected stay one week on average

Secondary Outcomes (2)

• Length of stay

  While patient in-hospital, expected stay one week on average

• Abdominal decompression

  While patient in-hospital, expected stay one week on average

Study Arms (2)

Elevated Intra-abdominal Pressure

Patients with intra-abdominal pressure \> 12 mmHg at any time throughout admission

Other: No intervention

Normal Intra-abdominal Pressure

Patients with intra-abdominal pressure \< 12 mmHg throughout admission

Other: No intervention

Interventions

No intervention OTHER

Elevated Intra-abdominal Pressure; Normal Intra-abdominal Pressure

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adults (\>18 years of age) admitted to the intensive care unit at Victoria Hospital, London, Ontario who have a Foley catheter in-situ

You may qualify if:

• Foley catheter in-situ on admission

You may not qualify if:

• Contra-indication to bladder pressure measurement
• Home service asked that patient is not included
• Death within 24 priors of admission before bladder pressure measured
• No bladder pressure performed within 24 hours of admission
• Consent refused or unable to be obtained (lack of SDM, patient unable to provide)

Sponsors & Collaborators

• Western University, Canada: lead

Study Sites (1)

Victoria Hospital

London, Ontario, N6K 1C2, Canada

Location

Related Publications (1)

• Kirkpatrick AW, Roberts DJ, De Waele J, Jaeschke R, Malbrain ML, De Keulenaer B, Duchesne J, Bjorck M, Leppaniemi A, Ejike JC, Sugrue M, Cheatham M, Ivatury R, Ball CG, Reintam Blaser A, Regli A, Balogh ZJ, D'Amours S, Debergh D, Kaplan M, Kimball E, Olvera C; Pediatric Guidelines Sub-Committee for the World Society of the Abdominal Compartment Syndrome. Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome. Intensive Care Med. 2013 Jul;39(7):1190-206. doi: 10.1007/s00134-013-2906-z. Epub 2013 May 15.

  PMID: 23673399 BACKGROUND

MeSH Terms

Conditions

Intra-Abdominal Hypertension

Condition Hierarchy (Ancestors)

Compartment Syndromes; Muscular Diseases; Musculoskeletal Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Kelly N Vogt, MD

  Western University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident

Study Record Dates

• First Submitted: July 30, 2015
• First Posted: August 3, 2015
• Study Start: September 1, 2015
• Primary Completion: January 30, 2016
• Study Completion: May 30, 2016
• Last Updated: August 27, 2018

Record last verified: 2018-08

Locations

CA (1)