Mealtime Walking Study to Improve Postprandial Metabolic Response
1 other identifier
interventional
10
0 countries
N/A
Brief Summary
This randomized crossover trial will investigate the metabolic responses following the consumption of a bagel+juice meal under 3 conditions: control, fiber (positive control), and postmeal walk in15 healthy adults. It is hypothesized that the postmeal walk will reduce glycemia, insulinemia, and oxidative stress similar to fiber.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Sep 2014
Shorter than P25 for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 17, 2014
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 14, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
March 10, 2015
CompletedFirst Submitted
Initial submission to the registry
July 31, 2020
CompletedFirst Posted
Study publicly available on registry
August 5, 2020
CompletedJuly 23, 2021
July 1, 2021
5 months
July 31, 2020
July 19, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Postprandial glycemia
incremental area under curve
4 hours
postprandial insulinemia
incremental area under curve
4 hours
Secondary Outcomes (3)
postprandial oxidative stress
4 hours
postprandial oxidative stress
4 hours
postprandial oxidative stress
4 hours
Study Arms (3)
Control
PLACEBO COMPARATORTest meal \[bagel with butter (20 g) and apple juice (240 ml) with added sugar (24 g)\] The meal was a total of 640 kcal (100 g carbohydrate, 21 g fat, 10 g protein. Participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption. One week later the test meal was consumed with fiber (36 g, Metamucil powder, Procter\&Gamble, Cincinnati, OH) added to the apple juice (active) and participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption . One week later participants were given 5 minutes to transition to the treadmill following consumption of the test meal and began walking on a motorized treadmill at their calculated preferred walking speed for 15 minutes (experimental). Afterwards participants remained seated in the laboratory with minimal activity for the remainder of the four hours following test meal consumption
Fiber
ACTIVE COMPARATORTest meal \[bagel with butter (20 g) and apple juice (240 ml) with added sugar (24 g)\] The meal was a total of 640 kcal (100 g carbohydrate, 21 g fat, 10 g protein. 9 grams of soluble viscous fiber from psyllium husk (36 g, Metamucil powder, Procter\&Gamble, Cincinnati, OH) was mixed with the apple juice. Participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption. One week later participants were given 5 minutes to transition to the treadmill following consumption of the test meal and began walking on a motorized treadmill at their calculated preferred walking speed for 15 minutes (experimental). Afterwards participants remained seated in the laboratory with minimal activity for the remainder of the four hours following test meal consumption. One week later the test meal was consumed, and participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption (placebo).
Walk
EXPERIMENTALTest meal \[bagel with butter (20 g) and apple juice (240 ml) with added sugar (24 g)\] The meal was a total of 640 kcal (100 g carbohydrate, 21 g fat, 10 g protein. Participants were given 5 minutes to transition to the treadmill following consumption of the test meal and began walking on a motorized treadmill at their calculated preferred walking speed for 15 minutes. Afterwards participants remained seated in the laboratory with minimal activity for the remainder of the four hours following test meal consumption One week later the test meal was consumed, and participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption (placebo comparator). One week later the test meal was consumed with fiber (36 g, Metamucil powder, Procter\&Gamble, Cincinnati, OH) added to the apple juice and participants remained seated in the laboratory with minimal activity for the four hours following test meal consumption (active comparator).
Interventions
Eligibility Criteria
You may qualify if:
- obese (BMI ≥ 30 kg/m2)
- nonsmoking
- sedentary
- fasting capillary blood glucose that measured from 5.6 to 6.9 mmol/L
You may not qualify if:
- answered "yes" to any of the questions on the "Par-Q \& You" questionnaire
- refused to discontinue antioxidant supplement use for several weeks prior to and during the study
- prescribed medication use (unless use was consistent for the 3 months prior to the study and intake remained consistent throughout the study duration)
- food allergies or medical conditions that impacted normal functioning of the gastrointestinal tract
Contact the study team to confirm eligibility.
Sponsors & Collaborators
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor and Associate Dean
Study Record Dates
First Submitted
July 31, 2020
First Posted
August 5, 2020
Study Start
September 17, 2014
Primary Completion
February 14, 2015
Study Completion
March 10, 2015
Last Updated
July 23, 2021
Record last verified: 2021-07
Data Sharing
- IPD Sharing
- Will not share