NCT03400774

Brief Summary

This study aims to investigate the effect of moderate intensity stair-climbing bouts of various durations on postprandial blood glucose. Participants will perform a standard oral glucose tolerance test (OGTT) using 75g of dextrose and with fingerstick blood glucose measurements at baseline and every 15 minutes after consuming the drink for one hour. On separate subsequent visits, participants will perform the same OGTT combined with three stair-climbing bouts lasting 1, 3, and 10 minutes starting 27, 25, and 18 minutes respectively after finishing the drink. Participants performed maximal aerobic capacity (VO2max) using a ramp treadmill test in order to assess the relative intensity of each stairclimbing trial.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2016

Shorter than P25 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 23, 2016

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 31, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2016

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

December 14, 2017

Completed
1 month until next milestone

First Posted

Study publicly available on registry

January 17, 2018

Completed
Last Updated

January 17, 2018

Status Verified

January 1, 2018

Enrollment Period

4 months

First QC Date

December 14, 2017

Last Update Submit

January 15, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Postprandial Blood Glucose

    Postprandial blood glucose after various durations of stair-climbing

    1 hour

Study Arms (4)

Control

OTHER

Oral glucose tolerance test with no stair-climbing

Other: Stair-climbing

1 minute

EXPERIMENTAL

Oral glucose tolerance test with 1 minute of stair-climbing

Other: Stair-climbing

3 minutes

EXPERIMENTAL

Oral glucose tolerance test with 3 minutes stair-climbing

Other: Stair-climbing

10 minutes

ACTIVE COMPARATOR

Oral glucose tolerance test with 10 minutes stair-climbing

Other: Stair-climbing

Interventions

Short bouts of moderate intensity stair-climbing

1 minute10 minutes3 minutesControl

Eligibility Criteria

Age18 Years - 45 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Defined as low risk per the American College of Sports Medicine (ACSM, Guidelines for Exercise Testing \& Exercise Prescription, 20014 pg 30)
  • Physical Activity Recall Questionnaire (PAR-Q) screening

You may not qualify if:

  • Glucose intolerance
  • Diabetes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Bartholomae EM, Moore J, Ward K, Kressler J. Sex differences in postprandial glucose response to short bouts of exercise: A randomized controlled trial. J Sci Med Sport. 2019 Feb;22(2):181-185. doi: 10.1016/j.jsams.2018.07.009. Epub 2018 Jul 20.

MeSH Terms

Conditions

Hyperglycemia

Interventions

Stair Climbing

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic Diseases

Intervention Hierarchy (Ancestors)

WalkingLocomotionMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaExerciseMotor Activity

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Jochen Kressler

Study Record Dates

First Submitted

December 14, 2017

First Posted

January 17, 2018

Study Start

March 23, 2016

Primary Completion

July 31, 2016

Study Completion

July 31, 2016

Last Updated

January 17, 2018

Record last verified: 2018-01