NCT05699395

Brief Summary

This is an observational study that establishes a cohort of patients with high risk chest pain who have been identified by CTA for aortic dissection. We then used this cohort to validate the accuracy of identifying aortic dissection based on extremity oximetry and Doppler waveforms.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 23, 2022

Completed
8 days until next milestone

Study Start

First participant enrolled

December 1, 2022

Completed
2 months until next milestone

First Posted

Study publicly available on registry

January 26, 2023

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2025

Completed
Last Updated

January 26, 2023

Status Verified

November 1, 2022

Enrollment Period

2.1 years

First QC Date

November 23, 2022

Last Update Submit

January 25, 2023

Conditions

Aortic Dissection

Outcome Measures

Primary Outcomes (1)

  • Diagnosis of aortic dissection

    aortic dissection confirmed by CTA

    First 24-hours during emergency dapartment stay

Study Arms (2)

Aortic Dissection

Diagnostic Test: Non interventional

Non Aortic Dissection

Diagnostic Test: Non interventional

Interventions

Non interventionalDIAGNOSTIC_TEST

No intervention

Aortic DissectionNon Aortic Dissection

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

High risk chest pain patients

You may qualify if:

  • High risk chest pain with CTA

You may not qualify if:

  • shock
  • coma
  • severe peripheral vascular diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zhongshan Hospital, Fudan University

Shanghai, China

RECRUITING

MeSH Terms

Conditions

Aortic Dissection

Condition Hierarchy (Ancestors)

Dissection, Blood VesselAneurysmVascular DiseasesCardiovascular DiseasesAcute Aortic SyndromeAortic Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 23, 2022

First Posted

January 26, 2023

Study Start

December 1, 2022

Primary Completion

December 31, 2024

Study Completion

May 31, 2025

Last Updated

January 26, 2023

Record last verified: 2022-11

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)