Biological Sample Collection for Research and Biobanking

NCT04270604 | Terminated

• 2 other identifiers: 10-00520112091
• Study Type: observational
• Target: 1,279
• Locations: 1 country
• Sites: 1

Brief Summary

The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to study different conditions and diseases by using cells from the body (such as skin or blood cells). NYSCF uses these samples to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and/or store these samples for future use. Through this research, scientists hope to identify future treatments or even cures.

Conditions

Parkinson Disease; Diabetes Mellitus, Type 1; Macular Degeneration; ALS; Cancer; Alzheimer Disease; Huntington Disease

Keywords

stem cell; observational; biobank; disease modeling; genetics

Outcome Measures

Primary Outcomes (1)

• Establishment of a diverse bank of biological samples, stem cell lines, derivatives, and associated information.

  There are no primary endpoints planned for this biobank; endpoints will be specific to research projects that utilize samples/data contained in the biobank. Projects may investigate the biology, etiology, manifestations, progression, risk factors, genetic underpinnings, and treatment of diseases, conditions, and traits.

  Baseline

Interventions

Biological sample collection OTHER

Biological sample collection for biobanking and research

Eligibility Criteria

• Age: 1 Month - 100 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Individuals with a diagnosis of one or more of the listed conditions. Individuals with a known genetic mutation, with or without a diagnosed condition. Individuals without a genetic mutation or condition to serve as healthy controls (a comparison group for those with conditions).

You may qualify if:

• Age
• years or older or
• Minor with parent/guardian consent
• Biological Sample Collection
• Able and willing to provide:
• new samples of blood, skin, and/or saliva specifically for use in this study and/or
• excess/leftover samples, cell lines, and/or derivatives that were (or will be) collected for reasons other than this study

You may not qualify if:

• Non-English speaking
• Wards of the state
• For skin samples collected specifically for this study: history of keloid formation, bleeding disorder, allergy to the anesthetic, or anticoagulation use that precludes sample collection.
• For blood samples collected specifically for this study: bleeding disorder, or other medical condition, if the subject's condition increases the risks associated with blood collection.
• For saliva samples: inability to produce sufficient saliva or has a condition that precludes sample collection (such as severe trismus).
• For prospective samples: refuse to adhere to NYSCF's and/or collaborating site's COVID-19 safety protocols during the COVID-19 pandemic.

Sponsors & Collaborators

• New York Stem Cell Foundation Research Institute: lead

Study Sites (1)

New York Stem Cell Foundation Research Institute

New York, New York, 10019, United States

Location

Related Links

• New York Stem Cell Foundation Website

Biospecimen

Retention: SAMPLES WITH DNA

Skin biopsy (2-3mm) and/or blood (up to 50 mL); saliva; excess/leftover biospecimens that were (or will be) collected for other purposes (e.g., medical procedure)

MeSH Terms

Conditions

Parkinson Disease; Diabetes Mellitus, Type 1; Macular Degeneration; Neoplasms; Alzheimer Disease; Huntington Disease

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Diabetes Mellitus; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases; Autoimmune Diseases; Immune System Diseases; Retinal Degeneration; Retinal Diseases; Eye Diseases; Dementia; Tauopathies; Neurocognitive Disorders; Mental Disorders; Chorea; Dyskinesias; Heredodegenerative Disorders, Nervous System; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Cognition Disorders

Study Officials

• Laura Andres-Martin

  New York Stem Cell Foundation Research Institute

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Senior Research Investigator

Study Record Dates

• First Submitted: December 20, 2019
• First Posted: February 17, 2020
• Study Start: February 6, 2012
• Primary Completion: November 27, 2023
• Study Completion: November 27, 2023
• Last Updated: August 2, 2024

Record last verified: 2024-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)