Macular Degeneration
277
18
23
168
Key Insights
Highlights
Success Rate
82% trial completion
Published Results
61 trials with published results (22%)
Research Maturity
168 completed trials (61% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 62/100
13.0%
36 terminated out of 277 trials
82.4%
-4.1% vs benchmark
20%
56 trials in Phase 3/4
36%
61 of 168 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 168 completed trials
Clinical Trials (277)
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
A Randomized, Double Masked, Parallel Group, Dose-finding Study to Evaluate SYL1801 in Patients With Neovascular Age-related Macular Degeneration (AMD)
A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003)
Artificial Intelligence-assisted Diagnosis in Ophthalmology
Factors in Learning And Plasticity: Healthy Vision
Factors in Learning And Plasticity: Macular Degeneration
Study of Zifibancimig in Participants With Neovascular Age-related Macular Degeneration
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects With Dry AMD
Evaluate the Efficacy of Faricimab in Patients With Neovascular Age-related Macular Degeneration
Learning Study: Improving Vision in Adults With Macular Degeneration
Natural History Study of Inherited Retinal Diseases
Ranibizumab and Reduced Fluence PDT for AMD
A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Scotoma Perimetry Oculomotor Training
A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)
Remapping Text in Sentence and Word Tasks to Aid Reading With Central Vision Loss
Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study