Key Insights

Highlights

Success Rate

78% trial completion

Published Results

20 trials with published results (19%)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 59/100

Termination Rate

13.0%

14 terminated out of 108 trials

Success Rate

77.8%

-8.8% vs benchmark

Late-Stage Pipeline

6%

7 trials in Phase 3/4

Results Transparency

41%

20 of 49 completed with results

Key Signals

20 with results78% success14 terminated

Data Visualizations

Phase Distribution

72Total
Not Applicable (30)
P 1 (19)
P 2 (16)
P 3 (7)

Trial Status

Completed49
Recruiting20
Terminated14
Unknown9
Not Yet Recruiting8
Active Not Recruiting5

Trial Success Rate

77.8%

Benchmark: 86.6%

Based on 49 completed trials

Clinical Trials (108)

Showing 20 of 20 trials
NCT05163886Phase 2Completed

Study of Safety, Tolerability, and Biological Activity of LAM-002A in C9ORF72-Associated Amyotrophic Lateral Sclerosis

NCT04396873Phase 1Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

NCT05602142Phase 1Not Yet RecruitingPrimary

Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS

NCT05151471Phase 3TerminatedPrimary

Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS

NCT06743776UnknownPrimary

Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS

NCT06377033Not ApplicableRecruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

NCT06286917Not ApplicableActive Not Recruiting

Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency

NCT07341334Not Yet Recruiting

Digital Speech Markers for Monitoring ALS in Spanish Speakers

NCT06735014Recruiting

Multicenter ALS Imaging Study

NCT07739134Active Not Recruiting

Multimodal Tracking of Therapy Activity and Effort During Rehabilitation

NCT07400393Not Yet RecruitingPrimary

Healey ALS MyMatch Common Screening Protocol

NCT05568615Phase 3CompletedPrimary

Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects With ALS

NCT04165824Phase 3CompletedPrimary

Safety Study of Oral Edaravone Administered in Subjects With ALS

NCT04569084Phase 3TerminatedPrimary

Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS

NCT06453668Phase 1TerminatedPrimary

A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients

NCT07193953Phase 1Active Not Recruiting

Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)

NCT07688239Phase 2Not Yet Recruiting

The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal Foralumab

NCT04259255Completed

Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)

NCT05271435CompletedPrimary

Digital Tools for Assessment of Motor Functions and Falls in ALS

NCT02795052Not ApplicableRecruiting

Neurologic Stem Cell Treatment Study

Scroll to load more

Research Network

Activity Timeline