ALS
108
20
25
49
Key Insights
Highlights
Success Rate
78% trial completion
Published Results
20 trials with published results (19%)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 59/100
13.0%
14 terminated out of 108 trials
77.8%
-8.8% vs benchmark
6%
7 trials in Phase 3/4
41%
20 of 49 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.6%
Based on 49 completed trials
Clinical Trials (108)
Study of Safety, Tolerability, and Biological Activity of LAM-002A in C9ORF72-Associated Amyotrophic Lateral Sclerosis
PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Study of [11C]CPPC as a Clinical PET Radioligand Biomarker of Microglial Activation in ALS
Efficacy and Safety Extension Study of Oral Edaravone Administered in Subjects With ALS
Scalable Expanded Access With Analysis of Neurofilament and Other Biomarkers for Ibudilast in ALS
Using the EHR to Advance Genomic Medicine Across a Diverse Health System
Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency
Digital Speech Markers for Monitoring ALS in Spanish Speakers
Multicenter ALS Imaging Study
Multimodal Tracking of Therapy Activity and Effort During Rehabilitation
Healey ALS MyMatch Common Screening Protocol
Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects With ALS
Safety Study of Oral Edaravone Administered in Subjects With ALS
Efficacy and Safety Study of Oral Edaravone Administered in Subjects With ALS
A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients
Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)
The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal Foralumab
Radicava® (Edaravone) Findings in Biomarkers From ALS (REFINE-ALS)
Digital Tools for Assessment of Motor Functions and Falls in ALS
Neurologic Stem Cell Treatment Study