Efficacy Evaluation of Triple up® Collagen Drink on Skin Condition

NCT04225091 | Completed

• 1 other identifier: 19-098-B
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

To assess Triple up® Collagen Drink on skin condition improvement

Conditions

Skin Condition

Outcome Measures

Primary Outcomes (4)

• The change of skin moisture

  Corneometer® CM825 was utilized to measure skin moisture. Units: arbitrary Corneometer® units 0-120

  Change from Baseline skin moisture at 4 weeks

• The change of skin elasticity

  Cutometer® dual MPA 580 was utilized to measure skin elasticity (parameter R2). Units: μm penetration depth into the probe opening, expressed as curves

  Change from Baseline skin elasticity at 4 weeks

• The change of skin wrinkles

  VISIA Complexion Analysis System was utilized to measure wrinkles. Units: arbitrary units

  Change from Baseline skin wrinkles at 4 weeks

• The change of skin collagen density

  DermaLab® USB - 20 MHz High Freq. Ultrasound probe was utilized to scan and analyze skin collagen density. Units: Intensity score

  Change from Baseline skin collagen density at 4 weeks

Secondary Outcomes (2)

• The change of skin texture

  Change from Baseline skin texture at 4 weeks

• The change of skin pores

  Change from Baseline skin pores at 4 weeks

Study Arms (2)

Placebo drink

PLACEBO COMPARATOR

Dietary Supplement: Blank

Triple up® Collagen Drink

EXPERIMENTAL

Dietary Supplement: Testing product

Interventions

Testing product DIETARY_SUPPLEMENT

consume 1 bottle (50 mL) per day for 28 days

Also known as: Triple up® Collagen Drink

Triple up® Collagen Drink

Blank DIETARY_SUPPLEMENT

consume 1 bottle (50 mL) per day for 28 days

Also known as: Placebo drink

Placebo drink

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 20 years old

You may not qualify if:

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
• Vegetarian
• Subjects who have large spots (area \>3 square centimeter) or abnormal acne.

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy ＆ Science

Tainan, 71710, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

• Chia-Hua Liang

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 6, 2020
• First Posted: January 13, 2020
• Study Start: January 30, 2020
• Primary Completion: April 21, 2020
• Study Completion: May 7, 2020
• Last Updated: November 30, 2020

Record last verified: 2020-11

Locations

TW (1)