Efficacy Testing of VeCollal Products

NCT05789368 | Completed

• 1 other identifier: 22-112-A
• Study Type: interventional
• Target: 90
• Locations: 1 country
• Sites: 1

Brief Summary

To assess VeCollal formula on skin condition improvement

Conditions

Skin Condition

Outcome Measures

Primary Outcomes (4)

• The change of skin collagen density

  DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units

  Change from Baseline skin collagen density at 8 weeks

• The change of skin wrinkles

  VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units

  Change from Baseline skin wrinkles at 8 weeks

• The change of skin texture

  VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units

  Change from Baseline skin texture at 8 weeks

• The change of skin elasticity

  SoftPlus was utilized to measure skin elasticity. Units: arbitrary units

  Change from Baseline skin elasticity at 8 weeks

Secondary Outcomes (6)

• The change of skin melanin index

  Change from Baseline skin melanin index at 8 weeks

• The change of skin L* value

  Change from Baseline skin L* value at 8 weeks

• The change of skin erythema index

  Change from Baseline skin erythema index at 8 weeks

• The change of skin moisture

  Change from Baseline skin moisture index at 8 weeks

• The change of transepidermal water loss (TEWL)

  Change from Baseline skin TEWL at 8 weeks

Other Outcomes (5)

• The change of liver function biomarkers (AST, ALT) of blood

  Change from Baseline liver function biomarkers at 8 weeks

• The change of renal function biomarkers (creatinine, BUN) of blood

  Change from Baseline renal function biomarkers at 8 weeks

• The change of fasting blood glucose

  Change from Baseline blood glucose at 8 weeks

Study Arms (3)

Placebo sachet

PLACEBO COMPARATOR

consume 1 sachet per day

Dietary Supplement: Placebo sachet

VeCollal sachet

EXPERIMENTAL

consume 1 sachet per day

Dietary Supplement: VeCollal sachet

Collagen sachet

ACTIVE COMPARATOR

consume 1 sachet per day

Dietary Supplement: Collagen sachet

Interventions

Placebo sachet DIETARY_SUPPLEMENT

consume 1 sachet per day

Placebo sachet

VeCollal sachet DIETARY_SUPPLEMENT

consume 1 sachet per day

VeCollal sachet

Collagen sachet DIETARY_SUPPLEMENT

consume 1 sachet per day

Collagen sachet

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 20 years old

You may not qualify if:

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure (\> 3 hr/week) in the past 4 weeks.
• Constant drug use
• Students who are currently taking courses taught by the principal investigator of this trial.

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy ＆ Science

Tainan, 71710, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

• Chia-Hua Liang

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 16, 2023
• First Posted: March 29, 2023
• Study Start: February 6, 2023
• Primary Completion: April 30, 2023
• Study Completion: June 28, 2023
• Last Updated: November 9, 2023

Record last verified: 2023-11

Locations

TW (1)